Proton cyclotron for beam therapy application
Project of the proton cyclotron for a beam therapy application is now under development in Dzhelepov LNP JINR. Main parameters of this machine are already reported and discussed in the proceedings of the RUPAC04 [1] and RUPAC06 [2] and in “Applied Physics” magazine [3]. Dynamic characteristics of th...
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Національний науковий центр «Харківський фізико-технічний інститут» НАН України
2008
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| Цитувати: | Proton cyclotron for beam therapy application / Y.G. Alenitsky, A.A. Glazov, G.A. Karamysheva, S.A. Kostromin, L.M. Onischenko, E.V. Samsonov, S.B. Vorozhtsov, A.S. Vorozhtsov, N.L. Zaplatin // Вопросы атомной науки и техники. — 2008. — № 5. — С. 16-18. — Бібліогр.: 4 назв. — англ. |
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irk-123456789-1114952017-01-11T03:03:12Z Proton cyclotron for beam therapy application Alenitsky, Y.G. Glazov, A.A. Karamysheva, G.A. Kostromin, S.A. Onischenko, L.M. Samsonov, E.V. Vorozhtsov, S.B. Vorozhtsov, A.S. Zaplatin, N.L. Физика и техника ускорителей Project of the proton cyclotron for a beam therapy application is now under development in Dzhelepov LNP JINR. Main parameters of this machine are already reported and discussed in the proceedings of the RUPAC04 [1] and RUPAC06 [2] and in “Applied Physics” magazine [3]. Dynamic characteristics of the beam at the range of radii more than 100 cm are specified. Different variants of the protons energy increase are also discussed. У ЛЯП ОІЯД розробляється протонний циклотрон для променевої терапії, основні параметри систем прискорювача викладені в роботах, представлених на конференціях RUPAC04, RUPAC06 і у журналі "Прикладна фізика". У роботі уточнюються динамічні характеристики пучку в діапазоні радіусів R>100 см і розглядаються можливості збільшення енергії протонів. В ЛЯП ОИЯИ разрабатывается протонный циклотрон для лучевой терапии, основные параметры систем ускорителя изложены в работах, представленных на конференциях RUPAC04, RUPAC06 и в журнале «Прикладная физика». В работе уточняются динамические характеристики пучка в диапазоне радиусов R>100 см и рассматриваются возможности увеличения энергии протонов. 2008 Article Proton cyclotron for beam therapy application / Y.G. Alenitsky, A.A. Glazov, G.A. Karamysheva, S.A. Kostromin, L.M. Onischenko, E.V. Samsonov, S.B. Vorozhtsov, A.S. Vorozhtsov, N.L. Zaplatin // Вопросы атомной науки и техники. — 2008. — № 5. — С. 16-18. — Бібліогр.: 4 назв. — англ. 1562-6016 PACS 29.20.Hm http://dspace.nbuv.gov.ua/handle/123456789/111495 en Вопросы атомной науки и техники Національний науковий центр «Харківський фізико-технічний інститут» НАН України |
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Digital Library of Periodicals of National Academy of Sciences of Ukraine |
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Физика и техника ускорителей Физика и техника ускорителей |
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Физика и техника ускорителей Физика и техника ускорителей Alenitsky, Y.G. Glazov, A.A. Karamysheva, G.A. Kostromin, S.A. Onischenko, L.M. Samsonov, E.V. Vorozhtsov, S.B. Vorozhtsov, A.S. Zaplatin, N.L. Proton cyclotron for beam therapy application Вопросы атомной науки и техники |
| description |
Project of the proton cyclotron for a beam therapy application is now under development in Dzhelepov LNP JINR. Main parameters of this machine are already reported and discussed in the proceedings of the RUPAC04 [1] and RUPAC06 [2] and in “Applied Physics” magazine [3]. Dynamic characteristics of the beam at the range of radii more than 100 cm are specified. Different variants of the protons energy increase are also discussed. |
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Article |
| author |
Alenitsky, Y.G. Glazov, A.A. Karamysheva, G.A. Kostromin, S.A. Onischenko, L.M. Samsonov, E.V. Vorozhtsov, S.B. Vorozhtsov, A.S. Zaplatin, N.L. |
| author_facet |
Alenitsky, Y.G. Glazov, A.A. Karamysheva, G.A. Kostromin, S.A. Onischenko, L.M. Samsonov, E.V. Vorozhtsov, S.B. Vorozhtsov, A.S. Zaplatin, N.L. |
| author_sort |
Alenitsky, Y.G. |
| title |
Proton cyclotron for beam therapy application |
| title_short |
Proton cyclotron for beam therapy application |
| title_full |
Proton cyclotron for beam therapy application |
| title_fullStr |
Proton cyclotron for beam therapy application |
| title_full_unstemmed |
Proton cyclotron for beam therapy application |
| title_sort |
proton cyclotron for beam therapy application |
| publisher |
Національний науковий центр «Харківський фізико-технічний інститут» НАН України |
| publishDate |
2008 |
| topic_facet |
Физика и техника ускорителей |
| url |
http://dspace.nbuv.gov.ua/handle/123456789/111495 |
| citation_txt |
Proton cyclotron for beam therapy application / Y.G. Alenitsky, A.A. Glazov, G.A. Karamysheva, S.A. Kostromin, L.M. Onischenko, E.V. Samsonov, S.B. Vorozhtsov, A.S. Vorozhtsov, N.L. Zaplatin // Вопросы атомной науки и техники. — 2008. — № 5. — С. 16-18. — Бібліогр.: 4 назв. — англ. |
| series |
Вопросы атомной науки и техники |
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| fulltext |
PROTON CYCLOTRON FOR BEAM THERAPY APPLICATION
Yu.G. Alenitsky, A.A. Glazov, G.A. Karamysheva, S.A. Kostromin, L.M. Onischenko,
E.V. Samsonov, S.B. Vorozhtsov, A.S. Vorozhtsov, N.L. Zaplatin
Dzhelepov Laboratory of Nuclear Problems, Joint Institute for Nuclear Research
141980, str. Joliot-Curie, 6, Dubna, Russia
fax:+7-49621-66666
Project of the proton cyclotron for a beam therapy application is now under development in Dzhelepov LNP
JINR. Main parameters of this machine are already reported and discussed in the proceedings of the RUPAC04 [1]
and RUPAC06 [2] and in “Applied Physics” magazine [3]. Dynamic characteristics of the beam at the range of radii
more than 100 cm are specified. Different variants of the protons energy increase are also discussed.
PACS 29.20.Hm
INTRODUCTION
In practice of treatment on the medical beam LNP
JINR the beam with energy 170 MeV and current
Iр ~ 0.1 mkA most frequently are used. A six–cabin
medical facility has been developed in LNP JINR and
put into operation on the base of Phazotron beam. Origi-
nal methods and technologies for forming dose fields
have been developed and successfully applied in a clinic
as well as new methods of reconstructive proton tomog-
raphy for treatment of patients with the medical Pha-
sotron beams.
All attempts to reduce the beam energy extracted
from Phasotron need the significant financial expenses
for change its magnetic and accelerating systems. We
suppose, that it is more rational to create a new cyclotron
with the required parameters of beams and to assembly it
in the LNP JINR to use it in the medical complex. Under
the offered project it is also possible to create cyclotron
for other interested organizations.
THE BASIC PARAMETERS
OF CYCLOTRON
MAGNETIC SYSTEM
Isochronous cyclotron for proton therapy is proposed
to be created on the basis of a compact four sectors mag-
net with a circle return yoke having an outside diameter
5.2 m and height 2.4 m. Some types of the return yokes
were calculated to compare them.
General view of mathematical model of the bottom
part of such types of magnets is shown in the
Figs.1,a,b,c. The required configuration of a magnetic
field is formed by means of spiral and angular extent of
the sector shims depending on radius.
Fig.1,a. 3D view of the proton cyclotron C200p magnet-
ic system (circle return yoke)
Fig.1,b. 3D view of the proton cyclotron C200p magnet-
ic system (four symmetry return yoke)
Fig.1,c. 3D view of the proton cyclotron C200p magnet-
ic system (two symmetry return yoke)
Modeling of the cyclotron magnetic system was car-
ried out by means of the code Radia ver. 4.098 [4],
which works under Mathematica platform and calculates
magnetic field of the three-dimensional magnetic sys-
tems by a method of the integrated equations. As a mate-
rial of the magnet the steel − 10 was used.
The complete angular extent of one sector on a pole
is 55º, thus in valleys there is an opportunity to place 42º
rectilinear resonators.
Consideration of the magnets (see the Figs.1a,b,c)
has shown that the difference caused by the return yoke
form does not exceed 150 G of an average magnetic
field. Formation of the field in such range can be made
by means of the special steel shims.
For the consumer the important characteristics of in-
stallation are both the sizes and a technology of manu-
facturing of the project, and both operational conditions
− consumed energy and cost of service. We propose on
the base of our results, that the offered project С200р
with four symmetry return yoke (see Fig.1,b) is optimum
and that such installation can be created as a pilot project
of our institute.
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BEAM DYNAMICS
In the Figs.2-4 the dynamic characteristics of a beam
in the magnetic field calculated for magnet with circle
yoke (Fig.1,a) are shown. The frequencies of axial and
radial motion (see Fig.2) are in allowable limits.
Working point diagram along the acceleration in
C200р is presented in Fig.3. The point to point distance
is 10 MeV. The most dangerous resonance Qr-Qz=1 is
crossed two times at energies 130 and 190 MeV. Model-
ing of the particle dynamics showed that no axial ampli-
tude increase observed after the resonance (see below) if
no skew harmonics presented in magnetic field map.
Further computations have to define permissible limits
of such harmonics.
Fig.2. Betatron frequencies along radius
Proton resonance orbital frequency is 20.4545 MHz.
Particle axial motion along acceleration in the magnetic
field is shown in Fig.4 with no skew harmonics. Ampli-
tude of particle radial oscillation was 5 mm in these
computations. Change of the axial oscillations amplitude
corresponds to the dependence of axial betatron frequen-
cy on the radius.
Fig.3. Working point diagram
Fig.4. Particle axial motion
Maximal energy of the protons in this cyclotron is
limited by E≈200 MeV due to a resonance Qz= 0.5,
which arises at radius 1.35 m, (see Fig.3), where the av-
erage magnetic field begins to fall. It is connected with
the pole edge located near this region. To provide a
growing, isochronous field, the gap between sectors is
possible to reduce (example − C230 IBA), but this could
lead to the technical difficulties, or to increase a diame-
ter of the magnet pole.
For the medical centre LNP JINR the estimated en-
ergy of protons is sufficient. An increase of the protons
energy is possible at additional increase of the expenses
for creation of the installation.
RADIOFREQUENCY SYSTEM
Rectilinear on radius the accelerating resonators
which have angular extent 42º and 30º dee are used.
They are located in valleys, where the gap between poles
is 400 mm. The adjustment and excitation of resonators
is carried out through the coaxial lines. The central rod
located from above and from below is used for the dee
support. Parts of the lines, which leave for the size of
400 mm are placed in the channels of poles of the mag-
net. The basic parameters of high-frequency system were
obtained making use a three-dimensional code. For exci-
tation of the accelerating system it is proposed to use the
standard high-frequency generator on the suitable capac-
ity and frequency 81.8 MHz working on linkage feeder
(see Fig.5).
Fig.5. General view of the calculating model for accel-
erating system
EXTRACTION SYSTEM
The extraction system consists of the beam radial en-
hancement system, electrostatic sections, bending and
focusing magnetic elements. At the moment only central
ion extraction has been calculated. To study the beam
acceleration at final radii and the efficiency of the ex-
traction it is necessary to fulfill some additional calcula-
tions.
OTHER CYCLOTRON SYSTEMS
The design of the cyclotron vacuum chamber de-
pends on the form of the return yoke. In our opinion the
magnet with four return yokes is more convenient to
make technological service of the cyclotron.
Diagnostics of the parameters of accelerated beam is
carried out by three probes, one of them is on the en-
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trance of extraction channel. On the exit of electrostatic
section of the channel the fourth short probe is arranged.
In connection with a rather low required intensity of
the beam in this cyclotron, it is possible to use a Penning
ion source, which is moved from above in the centre of
cyclotron. Acceleration and the formation of the beam
during the first turns is carried out with the help of spe-
cial central optics.
CONCLUSIONS
The physical consideration of proton cyclotron on the
energy of about Ep ~200 MeV was given. This cyclotron
will provide all scientific and medical programs on the
medical beam of Dzhelepov Laboratory of Nuclear
Problem, Joint Institute for Nuclear Research.
REFERENCES
1. Yu.G. Alenitsky, et al. Cyclotron for beam therapy
application // XIX Russian Particles Accelerator
Conf. Proc. p.162-164, Dubna 2005.
2. Yu.G. Alenitsky, et al. Cyclotron for therapy applic-
ation (in Russian) // XX Russian Particles Accelerat-
or Conf. Proc. Novosibirsk, 2007, p.162-164.
3. Yu.G. Alenitsky, et al. Cyclotron for therapy applica-
tion (in Russian) // Applied Physics. 2005, №5, p.50-
54.
4. P. Elleaume, O. Chubar, J. Chavanne. Computing
3D Magnetic Field from Insertion Devices // Proc.
of the PAC97 Conference. May 1997, p.3509-3511.
Статья поступила в редакцию 16.08.2007 г.
ПРОТОННЫЙ ЦИКЛОТРОН ДЛЯ ЛУЧЕВОЙ ТЕРАПИИ
Ю.Г. Аленицкий, А.А. Глазов, Г.А. Карамышева, С.А. Костромин, Л.М. Онищенко, Е.В. Самсонов,
С.Б. Ворожцов, А.С. Ворожцов, Н.Л. Заплатин
В ЛЯП ОИЯИ разрабатывается протонный циклотрон для лучевой терапии, основные параметры систем
ускорителя изложены в работах, представленных на конференциях RUPAC04, RUPAC06 и в журнале «При-
кладная физика». В работе уточняются динамические характеристики пучка в диапазоне радиусов R>100 см
и рассматриваются возможности увеличения энергии протонов.
ПРОТОННИЙ ЦИКЛОТРОН ДЛЯ ПРОМЕНЕВОЇ ТЕРАПІЇ
Ю.Г. Аленицький, А.А. Глазов, Г.А. Карамишева, С.А. Костромін, Л.М. Онищенко, Е.В. Самсонов,
С.Б. Ворожцов, А.С. Ворожцов, Н.Л. Заплатін
У ЛЯП ОІЯД розробляється протонний циклотрон для променевої терапії, основні параметри систем
прискорювача викладені в роботах, представлених на конференціях RUPAC04, RUPAC06 і у журналі
"Прикладна фізика". У роботі уточнюються динамічні характеристики пучку в діапазоні радіусів R>100 см і
розглядаються можливості збільшення енергії протонів.
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PROBLEMS OF ATOMIC SCIENCE AND TECHNOLOGY. 2008. 5№
Series: Nuclear Physics Investigations (50), p.16-18
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Introduction
BEAM DYNAMICS
extraction system
other cyclotron systems
conclusions
References
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