Optimization of conditions for ⁶⁷Cu photonuclear production

Radiopharmaceuticals based on the ⁶⁷Cu isotope have found wide use in immunotherapy. The present paper analyzes the conditions of ⁶⁷Cu production by the ⁶⁸Zn(γ,p) ⁶⁷Cu reaction at an electron accelerator in relation to the target isotope and hot impurities yield, as well as the radiation risks. Cons...

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Бібліографічні деталі
Дата:2015
Автори: Dovbnya, A.N., Dolzhek, M.A., Pugachev, G.D., Repikhov, O.A., Torgovkin, A.V., Uvarov, V.L., Shestakova, V.S., Shramenko, B.I.
Формат: Стаття
Мова:English
Опубліковано: Національний науковий центр «Харківський фізико-технічний інститут» НАН України 2015
Назва видання:Вопросы атомной науки и техники
Теми:
Онлайн доступ:http://dspace.nbuv.gov.ua/handle/123456789/112372
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Назва журналу:Digital Library of Periodicals of National Academy of Sciences of Ukraine
Цитувати:Optimization of conditions for ⁶⁷Cu photonuclear production / A.N. Dovbnya, M.A. Dolzhek, G.D. Pugachev, O.A. Repikhov, A.V. Torgovkin, V.L. Uvarov, V.S. Shestakova, B.I. Shramenko // Вопросы атомной науки и техники. — 2015. — № 6. — С. 160-164. — Бібліогр.: 7 назв. — англ.

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Резюме:Radiopharmaceuticals based on the ⁶⁷Cu isotope have found wide use in immunotherapy. The present paper analyzes the conditions of ⁶⁷Cu production by the ⁶⁸Zn(γ,p) ⁶⁷Cu reaction at an electron accelerator in relation to the target isotope and hot impurities yield, as well as the radiation risks. Consideration has been given to some variants of the technological target 40 g in weight made from natural zinc, and one enriched up to 99% in the ⁶⁸Zn isotope. The target exposition to bremsstrahlung with end-point energy 30 and 60 MeV was studied. It has been found that the use of enriched target results in reduction of both the radiation risk (down to 10⁻⁴) and the scope of waste han-dling procedures.