Photonuclear production of Pm-149

• Дата: 2015
• Автори: Dikiy, N.P., Dovbnya, A.N., Lyashko, Yu.V., Medvedeva, E.P., Medvedev, D.V., Uvarov, V.L.
• Формат: Стаття
• Мова: English
• Опубліковано: Національний науковий центр «Харківський фізико-технічний інститут» НАН України 2015
• Назва видання: Вопросы атомной науки и техники
• Теми: Применение ядерных методов
• Онлайн доступ: http://dspace.nbuv.gov.ua/handle/123456789/112373
• Назва журналу: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Цитувати: Photonuclear production of Pm-149 / N.P. Dikiy, A.N. Dovbnya, Yu.V. Lyashko, E.P. Medvedeva, D.V. Medvedev, V.L. Uvarov // Вопросы атомной науки и техники. — 2015. — № 6. — С. 157-159. — Бібліогр.: 12 назв. — англ.

¹⁵³Sm is successfully used for palliative treatment of patients with bone metastases and pain. ¹⁵³Sm is being produced in the reactors by means of irradiating of ¹⁵²Sm. In radio-labelled radiopharmaceuticals per each isotope of ¹⁵³Sm contained about 1000 atoms of the ¹⁵²Sm, which greatly influence the kinetics of its transport into the tumor. Production of ¹⁴⁹Pm isotopes that do not contain impurities of other isotopes, it was implemented using photonuclear reactions. The characteristics ¹⁴⁹Pm is practically coincides with the parameters of ¹⁵³Sm. The irradiation of neodymium of natural isotopic composition was carried out by means of bremsstrahlung with a maximum energy of 12.5 MeV. For production of ¹⁴⁹Рm the reaction ¹⁵⁰Nd(γ,n)¹⁴⁹Nd (T1/2=1.73 hours) → ¹⁴⁹Pm was used. Reaction ¹⁴⁸Nd(γ,n)¹⁴⁷Nd (T1/2=10.93 days) → ¹⁴⁷Pm (T1/2=2.62 years) will lead to low activity ¹⁴⁷Pm provided daily extraction ¹⁴⁹Pm. The rare earth elements of cerium group successfully are separated in a multistage extraction column using a normal tributyl ester of phosphoric acid.