Structural fluctuations and aging processes in deeply frozen proteins
Frozen proteins are nonergodic systems and are subject to two types of structural motions, namely relaxation and fluctuation. Relaxation manifests itself in aging processes which slow the fluctuations. Within certain approximations we are able to experimentally separate the aging dynamics from the f...
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Дата: | 2003 |
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Автори: | , , |
Формат: | Стаття |
Мова: | English |
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Фізико-технічний інститут низьких температур ім. Б.І. Вєркіна НАН України
2003
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Назва видання: | Физика низких температур |
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Онлайн доступ: | http://dspace.nbuv.gov.ua/handle/123456789/128929 |
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Назва журналу: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
Цитувати: | Structural fluctuations and aging processes in deeply frozen proteins / J. Schlichter, V.V. Ponkratov, J. Friedrich // Физика низких температур. — 2003. — Т. 29, № 9-10. — С. 1049-1056. — Бібліогр.: 21 назв. — англ. |
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irk-123456789-1289292018-01-15T03:03:05Z Structural fluctuations and aging processes in deeply frozen proteins Schlichter, J. Ponkratov, V.V. Friedrich, J. Biological Systems at Low Temperatures Frozen proteins are nonergodic systems and are subject to two types of structural motions, namely relaxation and fluctuation. Relaxation manifests itself in aging processes which slow the fluctuations. Within certain approximations we are able to experimentally separate the aging dynamics from the fluctuation dynamics by introducing two time parameters, namely an aging time ta and a waiting time tw. Both processes follow power laws in time. The fluctuation dynamics shows features of universality characterized by a rather uniform exponent of 1/4. This universality features were shown to be possible due to a random walk on a 1D random trajectory in conformational phase space. A very interesting aspect of protein dynamics concerns the influence of the host solvent on structural motions of the protein cores. We present results for sugar solvents and discuss possible mechanisms. 2003 Article Structural fluctuations and aging processes in deeply frozen proteins / J. Schlichter, V.V. Ponkratov, J. Friedrich // Физика низких температур. — 2003. — Т. 29, № 9-10. — С. 1049-1056. — Бібліогр.: 21 назв. — англ. 0132-6414 PACS: 87.15.-v http://dspace.nbuv.gov.ua/handle/123456789/128929 en Физика низких температур Фізико-технічний інститут низьких температур ім. Б.І. Вєркіна НАН України |
institution |
Digital Library of Periodicals of National Academy of Sciences of Ukraine |
collection |
DSpace DC |
language |
English |
topic |
Biological Systems at Low Temperatures Biological Systems at Low Temperatures |
spellingShingle |
Biological Systems at Low Temperatures Biological Systems at Low Temperatures Schlichter, J. Ponkratov, V.V. Friedrich, J. Structural fluctuations and aging processes in deeply frozen proteins Физика низких температур |
description |
Frozen proteins are nonergodic systems and are subject to two types of structural motions, namely relaxation and fluctuation. Relaxation manifests itself in aging processes which slow the fluctuations. Within certain approximations we are able to experimentally separate the aging dynamics from the fluctuation dynamics by introducing two time parameters, namely an aging time ta and a waiting time tw. Both processes follow power laws in time. The fluctuation dynamics shows features of universality characterized by a rather uniform exponent of 1/4. This universality features were shown to be possible due to a random walk on a 1D random trajectory in conformational phase space. A very interesting aspect of protein dynamics concerns the influence of the host solvent on structural motions of the protein cores. We present results for sugar solvents and discuss possible mechanisms. |
format |
Article |
author |
Schlichter, J. Ponkratov, V.V. Friedrich, J. |
author_facet |
Schlichter, J. Ponkratov, V.V. Friedrich, J. |
author_sort |
Schlichter, J. |
title |
Structural fluctuations and aging processes in deeply frozen proteins |
title_short |
Structural fluctuations and aging processes in deeply frozen proteins |
title_full |
Structural fluctuations and aging processes in deeply frozen proteins |
title_fullStr |
Structural fluctuations and aging processes in deeply frozen proteins |
title_full_unstemmed |
Structural fluctuations and aging processes in deeply frozen proteins |
title_sort |
structural fluctuations and aging processes in deeply frozen proteins |
publisher |
Фізико-технічний інститут низьких температур ім. Б.І. Вєркіна НАН України |
publishDate |
2003 |
topic_facet |
Biological Systems at Low Temperatures |
url |
http://dspace.nbuv.gov.ua/handle/123456789/128929 |
citation_txt |
Structural fluctuations and aging processes in deeply frozen proteins / J. Schlichter, V.V. Ponkratov, J. Friedrich // Физика низких температур. — 2003. — Т. 29, № 9-10. — С. 1049-1056. — Бібліогр.: 21 назв. — англ. |
series |
Физика низких температур |
work_keys_str_mv |
AT schlichterj structuralfluctuationsandagingprocessesindeeplyfrozenproteins AT ponkratovvv structuralfluctuationsandagingprocessesindeeplyfrozenproteins AT friedrichj structuralfluctuationsandagingprocessesindeeplyfrozenproteins |
first_indexed |
2023-10-18T20:56:28Z |
last_indexed |
2023-10-18T20:56:28Z |
_version_ |
1796151508009484288 |