Tyrosine kinase inhibitors in treatment of fibrous histiocytoma
Aim: To describe potential beneficial effects of tyrosine kinase inhibitor in the treatment of unresectable/metastatic fibrous histiocytoma. Methods: We report a case of advanced stage fibrous histiocytoma with locally recurrent disease plus lung and bone metastatic deposits. Patient was treated w...
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| Видавець: | Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України |
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| Дата: | 2009 |
| Автори: | , , , , |
| Формат: | Стаття |
| Мова: | English |
| Опубліковано: |
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
2009
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| Назва видання: | Experimental Oncology |
| Теми: | |
| Онлайн доступ: | http://dspace.nbuv.gov.ua/handle/123456789/135111 |
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| Цитувати: | Tyrosine kinase inhibitors in treatment of fibrous histiocytoma / D. Mauri, C. Panou, A. Valachis, K. Kamposioras, L. Tsali // Experimental Oncology. — 2009. — Т. 31, № 1. — С. 60-61. — Бібліогр.: 18 назв. — англ. |
Репозиторії
Digital Library of Periodicals of National Academy of Sciences of Ukraine| id |
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irk-123456789-1351112018-06-15T03:10:12Z Tyrosine kinase inhibitors in treatment of fibrous histiocytoma Maur, D. Panou, C. Valachis, A. Kamposioras, K. Tsali, L. Short communications Aim: To describe potential beneficial effects of tyrosine kinase inhibitor in the treatment of unresectable/metastatic fibrous histiocytoma. Methods: We report a case of advanced stage fibrous histiocytoma with locally recurrent disease plus lung and bone metastatic deposits. Patient was treated with the tyrosine kinase inhibitor sunitinib. Results: Treatment with Sunitinib resulted in disease stabilization in the regional lesion and in good partial response for metastatic foci (reduction in number and size). After 13 months of treatment the patient is doing well with no tumor progression. Conclusions: This case appears to be one of the first documentations of beneficial effect and potential long-term benefit of TKIs in the treatment of fibrous histiocytoma. 2009 Article Tyrosine kinase inhibitors in treatment of fibrous histiocytoma / D. Mauri, C. Panou, A. Valachis, K. Kamposioras, L. Tsali // Experimental Oncology. — 2009. — Т. 31, № 1. — С. 60-61. — Бібліогр.: 18 назв. — англ. 1812-9269 http://dspace.nbuv.gov.ua/handle/123456789/135111 en Experimental Oncology Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України |
| institution |
Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| collection |
DSpace DC |
| language |
English |
| topic |
Short communications Short communications |
| spellingShingle |
Short communications Short communications Maur, D. Panou, C. Valachis, A. Kamposioras, K. Tsali, L. Tyrosine kinase inhibitors in treatment of fibrous histiocytoma Experimental Oncology |
| description |
Aim: To describe potential beneficial effects of tyrosine kinase inhibitor in the treatment of unresectable/metastatic fibrous histiocytoma.
Methods: We report a case of advanced stage fibrous histiocytoma with locally recurrent disease plus lung and bone
metastatic deposits. Patient was treated with the tyrosine kinase inhibitor sunitinib. Results: Treatment with Sunitinib resulted in
disease stabilization in the regional lesion and in good partial response for metastatic foci (reduction in number and size). After
13 months of treatment the patient is doing well with no tumor progression. Conclusions: This case appears to be one of the first
documentations of beneficial effect and potential long-term benefit of TKIs in the treatment of fibrous histiocytoma. |
| format |
Article |
| author |
Maur, D. Panou, C. Valachis, A. Kamposioras, K. Tsali, L. |
| author_facet |
Maur, D. Panou, C. Valachis, A. Kamposioras, K. Tsali, L. |
| author_sort |
Maur, D. |
| title |
Tyrosine kinase inhibitors in treatment of fibrous histiocytoma |
| title_short |
Tyrosine kinase inhibitors in treatment of fibrous histiocytoma |
| title_full |
Tyrosine kinase inhibitors in treatment of fibrous histiocytoma |
| title_fullStr |
Tyrosine kinase inhibitors in treatment of fibrous histiocytoma |
| title_full_unstemmed |
Tyrosine kinase inhibitors in treatment of fibrous histiocytoma |
| title_sort |
tyrosine kinase inhibitors in treatment of fibrous histiocytoma |
| publisher |
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України |
| publishDate |
2009 |
| topic_facet |
Short communications |
| url |
http://dspace.nbuv.gov.ua/handle/123456789/135111 |
| citation_txt |
Tyrosine kinase inhibitors in treatment of fibrous histiocytoma / D. Mauri, C. Panou, A. Valachis, K. Kamposioras, L. Tsali // Experimental Oncology. — 2009. — Т. 31, № 1. — С. 60-61. — Бібліогр.: 18 назв. — англ. |
| series |
Experimental Oncology |
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AT maurd tyrosinekinaseinhibitorsintreatmentoffibroushistiocytoma AT panouc tyrosinekinaseinhibitorsintreatmentoffibroushistiocytoma AT valachisa tyrosinekinaseinhibitorsintreatmentoffibroushistiocytoma AT kamposiorask tyrosinekinaseinhibitorsintreatmentoffibroushistiocytoma AT tsalil tyrosinekinaseinhibitorsintreatmentoffibroushistiocytoma |
| first_indexed |
2023-10-18T21:11:14Z |
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2023-10-18T21:11:14Z |
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