Ribonucleases. possible new approach in cancer therapy
In the review, the use of the ribonucleases for cancer therapy is discussed. Using of epigenetic mechanisms of regulation — blocking protein synthesis without affecting the DNA structure — is a promising direction in the therapy. The ribonucleases isolated from different sources, despite of simila...
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| Дата: | 2016 |
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| Автор: | |
| Формат: | Стаття |
| Мова: | English |
| Опубліковано: |
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
2016
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| Назва видання: | Experimental Oncology |
| Теми: | |
| Онлайн доступ: | http://dspace.nbuv.gov.ua/handle/123456789/136133 |
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| Назва журналу: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Цитувати: | Ribonucleases. possible new approach in cancer therapy / V.O. Shlyakhovenko // Experimental Oncology. — 2016 — Т. 38, № 1. — С. 2–8. — Бібліогр.: 47 назв. — англ. |
Репозитарії
Digital Library of Periodicals of National Academy of Sciences of Ukraine| id |
irk-123456789-136133 |
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irk-123456789-1361332018-06-16T03:11:28Z Ribonucleases. possible new approach in cancer therapy Shlyakhovenko, V.O. Reviews In the review, the use of the ribonucleases for cancer therapy is discussed. Using of epigenetic mechanisms of regulation — blocking protein synthesis without affecting the DNA structure — is a promising direction in the therapy. The ribonucleases isolated from different sources, despite of similar mechanism of enzymatic reactions, have different biological effects. The use of enzymes isolated from new sources, particularly from plants and fungi, shows promising results. In this article we discuss the new approach for the use of enzymes resistant to inhibitors and ribozymes, that is aimed at the destruction of the oncogene specific mRNA and the induction of apoptosis. 2016 Article Ribonucleases. possible new approach in cancer therapy / V.O. Shlyakhovenko // Experimental Oncology. — 2016 — Т. 38, № 1. — С. 2–8. — Бібліогр.: 47 назв. — англ. 1812-9269 http://dspace.nbuv.gov.ua/handle/123456789/136133 en Experimental Oncology Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України |
| institution |
Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| collection |
DSpace DC |
| language |
English |
| topic |
Reviews Reviews |
| spellingShingle |
Reviews Reviews Shlyakhovenko, V.O. Ribonucleases. possible new approach in cancer therapy Experimental Oncology |
| description |
In the review, the use of the ribonucleases for cancer therapy is discussed. Using of epigenetic mechanisms of regulation — blocking
protein synthesis without affecting the DNA structure — is a promising direction in the therapy. The ribonucleases isolated from different
sources, despite of similar mechanism of enzymatic reactions, have different biological effects. The use of enzymes isolated from new
sources, particularly from plants and fungi, shows promising results. In this article we discuss the new approach for the use of enzymes
resistant to inhibitors and ribozymes, that is aimed at the destruction of the oncogene specific mRNA and the induction of apoptosis. |
| format |
Article |
| author |
Shlyakhovenko, V.O. |
| author_facet |
Shlyakhovenko, V.O. |
| author_sort |
Shlyakhovenko, V.O. |
| title |
Ribonucleases. possible new approach in cancer therapy |
| title_short |
Ribonucleases. possible new approach in cancer therapy |
| title_full |
Ribonucleases. possible new approach in cancer therapy |
| title_fullStr |
Ribonucleases. possible new approach in cancer therapy |
| title_full_unstemmed |
Ribonucleases. possible new approach in cancer therapy |
| title_sort |
ribonucleases. possible new approach in cancer therapy |
| publisher |
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України |
| publishDate |
2016 |
| topic_facet |
Reviews |
| url |
http://dspace.nbuv.gov.ua/handle/123456789/136133 |
| citation_txt |
Ribonucleases. possible new approach in cancer therapy / V.O. Shlyakhovenko // Experimental Oncology. — 2016 — Т. 38, № 1. — С. 2–8. — Бібліогр.: 47 назв. — англ. |
| series |
Experimental Oncology |
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AT shlyakhovenkovo ribonucleasespossiblenewapproachincancertherapy |
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2023-10-18T21:13:15Z |
| last_indexed |
2023-10-18T21:13:15Z |
| _version_ |
1796152235448598528 |