Blood viscosity in patients with diffuse large B cell non-Hodgkin’s lymphoma

• Дата: 2006
• Автори: Utkan, G., Tek, I., Kocer, M., Muallaoglu, S., Durnalı, A.G., Arslan, U.Y., Celenkoglu, G., Tokluoglu, S., Alkis, N.
• Формат: Стаття
• Мова: English
• Опубліковано: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2006
• Назва видання: Experimental Oncology
• Теми: Short communications
• Онлайн доступ: http://dspace.nbuv.gov.ua/handle/123456789/137926
• Назва журналу: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Цитувати: Blood viscosity in patients with diffuse large B cell non-Hodgkin’s lymphoma / G. Utkan, I. Tek, M. Kocer, S. Muallaoglu, A.G. Durnalı, U.Y. Arslan, G. Celenkoglu, S. Tokluoglu, N. Alkis // Experimental Oncology. — 2006. — Т. 28, № 4. — С. 326-327. — Бібліогр.: 9 назв. — англ.

The aim of the study was to evaluate blood viscosity as possible marker of disease progression in patients with newly diagnosed non-Hodgkin’s lymphoma (NHL). Methods: The viscosity of blood samples from 20 patients with newly diagnosed aggressive NHL (stage I, n = 7; stage II, n = 4; stage III, n = 7; stage IV, n = 2) was analyzed using Brookfield DV-II + (USA) machine. Results: Blood viscosity in NHL patients (median: 5.5 ± 1.46 miliPascal) inversely correlated with lactatdehydrogenase (LDH) level, international prognostic index (IPI) score, and stage (p = 0.02, r= –0.51; p = 0.03, r= –0.63; and p = 0.04, r= –0.45, respectively) and positively correlated with hemoglobin level (p = 0.02, r = 0.65)). Conclusion: According to our data, blood viscosity may be considered as a follow up marker in NHL patients along with LDH level or sedimentation rate.