Blood viscosity in patients with diffuse large B cell non-Hodgkin’s lymphoma

The aim of the study was to evaluate blood viscosity as possible marker of disease progression in patients with newly diagnosed non-Hodgkin’s lymphoma (NHL). Methods: The viscosity of blood samples from 20 patients with newly diagnosed aggressive NHL (stage I, n = 7; stage II, n = 4; stage III, n =...

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Дата:2006
Автори: Utkan, G., Tek, I., Kocer, M., Muallaoglu, S., Durnalı, A.G., Arslan, U.Y., Celenkoglu, G., Tokluoglu, S., Alkis, N.
Формат: Стаття
Мова:English
Опубліковано: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2006
Назва видання:Experimental Oncology
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Онлайн доступ:http://dspace.nbuv.gov.ua/handle/123456789/137926
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Назва журналу:Digital Library of Periodicals of National Academy of Sciences of Ukraine
Цитувати:Blood viscosity in patients with diffuse large B cell non-Hodgkin’s lymphoma / G. Utkan, I. Tek, M. Kocer, S. Muallaoglu, A.G. Durnalı, U.Y. Arslan, G. Celenkoglu, S. Tokluoglu, N. Alkis // Experimental Oncology. — 2006. — Т. 28, № 4. — С. 326-327. — Бібліогр.: 9 назв. — англ.

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Digital Library of Periodicals of National Academy of Sciences of Ukraine
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spelling irk-123456789-1379262018-06-18T03:11:25Z Blood viscosity in patients with diffuse large B cell non-Hodgkin’s lymphoma Utkan, G. Tek, I. Kocer, M. Muallaoglu, S. Durnalı, A.G. Arslan, U.Y. Celenkoglu, G. Tokluoglu, S. Alkis, N. Short communications The aim of the study was to evaluate blood viscosity as possible marker of disease progression in patients with newly diagnosed non-Hodgkin’s lymphoma (NHL). Methods: The viscosity of blood samples from 20 patients with newly diagnosed aggressive NHL (stage I, n = 7; stage II, n = 4; stage III, n = 7; stage IV, n = 2) was analyzed using Brookfield DV-II + (USA) machine. Results: Blood viscosity in NHL patients (median: 5.5 ± 1.46 miliPascal) inversely correlated with lactatdehydrogenase (LDH) level, international prognostic index (IPI) score, and stage (p = 0.02, r= –0.51; p = 0.03, r= –0.63; and p = 0.04, r= –0.45, respectively) and positively correlated with hemoglobin level (p = 0.02, r = 0.65)). Conclusion: According to our data, blood viscosity may be considered as a follow up marker in NHL patients along with LDH level or sedimentation rate. Цель: анализ вязкости крови в качестве маркера возможного маркера прогрессии заболевания у больных неходжкинской лимфомой (НХЛ). Методы: вязкость крови 20 пациентов НХЛ (стадия I, = 7; стадия II, = 4; стадия III, = 7; стадия  IV, n = 4) измеряли на приборе Brookfield DV-II + (США). Результаты: вязкость крови больных НХЛ (средняя величина: 5.5 ± 1.46 миллиПаскаль) находилась в обратной корреляции с уровнем лактатдегидрогеназы (ЛДГ), величиной международного прогностического индекса (IPI) и стадией заболевания (p = 0,02, r = –0,51; p = 0,03, r = –0,63; p = 0,04, r = –0,45 соответственно) и в прямой зависимости от уровня гемоглобина (p = 0,02, = 0,65)). Выводы: согласно полученным данным, вязкость крови можно рассматривать в качестве маркера течения заболевания у больных НХЛ наряду с уровнем ЛДГ и показателем скорости оседания эритроцитов. 2006 Article Blood viscosity in patients with diffuse large B cell non-Hodgkin’s lymphoma / G. Utkan, I. Tek, M. Kocer, S. Muallaoglu, A.G. Durnalı, U.Y. Arslan, G. Celenkoglu, S. Tokluoglu, N. Alkis // Experimental Oncology. — 2006. — Т. 28, № 4. — С. 326-327. — Бібліогр.: 9 назв. — англ. 1812-9269 http://dspace.nbuv.gov.ua/handle/123456789/137926 en Experimental Oncology Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
institution Digital Library of Periodicals of National Academy of Sciences of Ukraine
collection DSpace DC
language English
topic Short communications
Short communications
spellingShingle Short communications
Short communications
Utkan, G.
Tek, I.
Kocer, M.
Muallaoglu, S.
Durnalı, A.G.
Arslan, U.Y.
Celenkoglu, G.
Tokluoglu, S.
Alkis, N.
Blood viscosity in patients with diffuse large B cell non-Hodgkin’s lymphoma
Experimental Oncology
description The aim of the study was to evaluate blood viscosity as possible marker of disease progression in patients with newly diagnosed non-Hodgkin’s lymphoma (NHL). Methods: The viscosity of blood samples from 20 patients with newly diagnosed aggressive NHL (stage I, n = 7; stage II, n = 4; stage III, n = 7; stage IV, n = 2) was analyzed using Brookfield DV-II + (USA) machine. Results: Blood viscosity in NHL patients (median: 5.5 ± 1.46 miliPascal) inversely correlated with lactatdehydrogenase (LDH) level, international prognostic index (IPI) score, and stage (p = 0.02, r= –0.51; p = 0.03, r= –0.63; and p = 0.04, r= –0.45, respectively) and positively correlated with hemoglobin level (p = 0.02, r = 0.65)). Conclusion: According to our data, blood viscosity may be considered as a follow up marker in NHL patients along with LDH level or sedimentation rate.
format Article
author Utkan, G.
Tek, I.
Kocer, M.
Muallaoglu, S.
Durnalı, A.G.
Arslan, U.Y.
Celenkoglu, G.
Tokluoglu, S.
Alkis, N.
author_facet Utkan, G.
Tek, I.
Kocer, M.
Muallaoglu, S.
Durnalı, A.G.
Arslan, U.Y.
Celenkoglu, G.
Tokluoglu, S.
Alkis, N.
author_sort Utkan, G.
title Blood viscosity in patients with diffuse large B cell non-Hodgkin’s lymphoma
title_short Blood viscosity in patients with diffuse large B cell non-Hodgkin’s lymphoma
title_full Blood viscosity in patients with diffuse large B cell non-Hodgkin’s lymphoma
title_fullStr Blood viscosity in patients with diffuse large B cell non-Hodgkin’s lymphoma
title_full_unstemmed Blood viscosity in patients with diffuse large B cell non-Hodgkin’s lymphoma
title_sort blood viscosity in patients with diffuse large b cell non-hodgkin’s lymphoma
publisher Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
publishDate 2006
topic_facet Short communications
url http://dspace.nbuv.gov.ua/handle/123456789/137926
citation_txt Blood viscosity in patients with diffuse large B cell non-Hodgkin’s lymphoma / G. Utkan, I. Tek, M. Kocer, S. Muallaoglu, A.G. Durnalı, U.Y. Arslan, G. Celenkoglu, S. Tokluoglu, N. Alkis // Experimental Oncology. — 2006. — Т. 28, № 4. — С. 326-327. — Бібліогр.: 9 назв. — англ.
series Experimental Oncology
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first_indexed 2023-10-18T21:16:45Z
last_indexed 2023-10-18T21:16:45Z
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