Genetic and epigenetic changes of NKIRAS1 gene in human renal cell carcinomas

• Main Authors: Gerashchenko, G.V., Bogatyrova, O.O., Rudenko, E.E., Kondratov, A.G., Gordiyuk, V.V., Zgonnyk, Y.M., Vozianov, O.F., Pavlova, T.V., Zabarovsky, E.R., Rynditch, A.V., Kashuba, V.I.
• Format: Article
• Language: English
• Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2010
• Series: Experimental Oncology
• Subjects: Original contributions
• Online Access: http://dspace.nbuv.gov.ua/handle/123456789/138607

Renal cell carcinoma (RCC) is the most common malignant tumor of kidney associated with the worst clinical outcome. No molecular markers for RCC diagnostics and prognosis that could be applied in clinics were described yet. Large-scale screening of 3p human chromosome genes/loci in RCC and histologi...