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Age-related function of tumor suppressor gene TP53:contribution to cancer risk and progression
Aim: To examine the influence of combined genotypes of TP53 (exon 4, intron 3, intron 6) and XRCC1 (codon 10) on lung cancer age of onset. Methods: TP53 polymorphisms in codon 72 of exon 4 (Arg72Pro), in intron 3 (16 bp duplication), in intron 6 (G/A transition) and XRCC1 polymorphism in codon 10 (A...
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Main Authors: | Cherdyntseva, N.V., Gervas, P.A., Litvyakov, N.V., Stakcheeva, M.N., Ponomaryeva, A.A., Dobrodeev, A.Yu., Denisov, E.V., Belyavskaya, V.A., Choinzonov, E.L. |
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Format: | Article |
Language: | English |
Published: |
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
2010
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Series: | Experimental Oncology |
Subjects: | |
Online Access: | http://dspace.nbuv.gov.ua/handle/123456789/138611 |
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