Mobile genetic elements and cancer. From mutations to gene therapy
In the present review, an association between cancer and the activity of the non-LTR retroelements L1, Alu, and SVA, as well as endogenous retroviruses, in the human genome, is analyzed. Data suggesting that transposons have been involved in embryogenesis and malignization processes, are presented....
Збережено в:
| Дата: | 2011 |
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| Автори: | , , |
| Формат: | Стаття |
| Мова: | English |
| Опубліковано: |
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
2011
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| Назва видання: | Experimental Oncology |
| Теми: | |
| Онлайн доступ: | http://dspace.nbuv.gov.ua/handle/123456789/138667 |
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| Назва журналу: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Цитувати: | Mobile genetic elements and cancer. From mutations to gene therapy / I.A. Kozeretska, S.V. Demydov, L.I. Ostapchenko // Experimental Oncology. — 2011. — Т. 33, № 4. — С. 198-205. — Бібліогр.: 114 назв. — англ. |
Репозитарії
Digital Library of Periodicals of National Academy of Sciences of Ukraine| id |
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irk-123456789-1386672018-06-20T03:09:50Z Mobile genetic elements and cancer. From mutations to gene therapy Kozeretska, I.A. Demydov, S.V. Ostapchenko, L.I. Reviews In the present review, an association between cancer and the activity of the non-LTR retroelements L1, Alu, and SVA, as well as endogenous retroviruses, in the human genome, is analyzed. Data suggesting that transposons have been involved in embryogenesis and malignization processes, are presented. Events that lead to the activation of mobile elements in mammalian somatic cells, as well as the use of mobile elements in genetic screening and cancer gene therapy, are reviewed. 2011 Article Mobile genetic elements and cancer. From mutations to gene therapy / I.A. Kozeretska, S.V. Demydov, L.I. Ostapchenko // Experimental Oncology. — 2011. — Т. 33, № 4. — С. 198-205. — Бібліогр.: 114 назв. — англ. 1812-9269 http://dspace.nbuv.gov.ua/handle/123456789/138667 en Experimental Oncology Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України |
| institution |
Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| collection |
DSpace DC |
| language |
English |
| topic |
Reviews Reviews |
| spellingShingle |
Reviews Reviews Kozeretska, I.A. Demydov, S.V. Ostapchenko, L.I. Mobile genetic elements and cancer. From mutations to gene therapy Experimental Oncology |
| description |
In the present review, an association between cancer and the activity of the non-LTR retroelements L1, Alu, and SVA, as well as endogenous retroviruses, in the human genome, is analyzed. Data suggesting that transposons have been involved in embryogenesis and malignization processes, are presented. Events that lead to the activation of mobile elements in mammalian somatic cells, as well as the use of mobile elements in genetic screening and cancer gene therapy, are reviewed. |
| format |
Article |
| author |
Kozeretska, I.A. Demydov, S.V. Ostapchenko, L.I. |
| author_facet |
Kozeretska, I.A. Demydov, S.V. Ostapchenko, L.I. |
| author_sort |
Kozeretska, I.A. |
| title |
Mobile genetic elements and cancer. From mutations to gene therapy |
| title_short |
Mobile genetic elements and cancer. From mutations to gene therapy |
| title_full |
Mobile genetic elements and cancer. From mutations to gene therapy |
| title_fullStr |
Mobile genetic elements and cancer. From mutations to gene therapy |
| title_full_unstemmed |
Mobile genetic elements and cancer. From mutations to gene therapy |
| title_sort |
mobile genetic elements and cancer. from mutations to gene therapy |
| publisher |
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України |
| publishDate |
2011 |
| topic_facet |
Reviews |
| url |
http://dspace.nbuv.gov.ua/handle/123456789/138667 |
| citation_txt |
Mobile genetic elements and cancer. From mutations to gene therapy / I.A. Kozeretska, S.V. Demydov, L.I. Ostapchenko // Experimental Oncology. — 2011. — Т. 33, № 4. — С. 198-205. — Бібліогр.: 114 назв. — англ. |
| series |
Experimental Oncology |
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2023-10-18T21:18:57Z |
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2023-10-18T21:18:57Z |
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