Translation control in apoptosis

Regulation of protein synthesis, although known for many decades, has only recently begun to be recognized as a critical control mechanism for the maintenance of cellular homeostasis and cellular stress response. One of the key advantages of translational control is the ability of cells to rapidly r...

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Видавець:Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
Дата:2012
Автори: Liwak, U., Faye, M.D., Holcik, M.
Формат: Стаття
Мова:English
Опубліковано: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2012
Назва видання:Experimental Oncology
Теми:
Онлайн доступ:http://dspace.nbuv.gov.ua/handle/123456789/139050
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Цитувати:Translation control in apoptosis / U. Liwak, M.D. Faye, M. Holcik // Experimental Oncology. — 2012. — Т. 34, № 3. — С. 218-230. — Бібліогр.: 123 назв. — англ.

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Digital Library of Periodicals of National Academy of Sciences of Ukraine
id irk-123456789-139050
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spelling irk-123456789-1390502018-06-20T03:10:26Z Translation control in apoptosis Liwak, U. Faye, M.D. Holcik, M. Reviews Regulation of protein synthesis, although known for many decades, has only recently begun to be recognized as a critical control mechanism for the maintenance of cellular homeostasis and cellular stress response. One of the key advantages of translational control is the ability of cells to rapidly reprogram the protein output in response to internal or external triggers. This is particularly important during cellular response to stress that may lead to apoptosis by providing cells with a fine tuning mechanism that tips the balance between cell survival or apoptosis. In the following review we highlight several distinct mechanisms of translation control and provide specific examples of translational control during apoptosis. This article is part of a Special Issue entitled “Apoptosis: Four Decades Later”. 2012 Article Translation control in apoptosis / U. Liwak, M.D. Faye, M. Holcik // Experimental Oncology. — 2012. — Т. 34, № 3. — С. 218-230. — Бібліогр.: 123 назв. — англ. 1812-9269 http://dspace.nbuv.gov.ua/handle/123456789/139050 en Experimental Oncology Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
institution Digital Library of Periodicals of National Academy of Sciences of Ukraine
collection DSpace DC
language English
topic Reviews
Reviews
spellingShingle Reviews
Reviews
Liwak, U.
Faye, M.D.
Holcik, M.
Translation control in apoptosis
Experimental Oncology
description Regulation of protein synthesis, although known for many decades, has only recently begun to be recognized as a critical control mechanism for the maintenance of cellular homeostasis and cellular stress response. One of the key advantages of translational control is the ability of cells to rapidly reprogram the protein output in response to internal or external triggers. This is particularly important during cellular response to stress that may lead to apoptosis by providing cells with a fine tuning mechanism that tips the balance between cell survival or apoptosis. In the following review we highlight several distinct mechanisms of translation control and provide specific examples of translational control during apoptosis. This article is part of a Special Issue entitled “Apoptosis: Four Decades Later”.
format Article
author Liwak, U.
Faye, M.D.
Holcik, M.
author_facet Liwak, U.
Faye, M.D.
Holcik, M.
author_sort Liwak, U.
title Translation control in apoptosis
title_short Translation control in apoptosis
title_full Translation control in apoptosis
title_fullStr Translation control in apoptosis
title_full_unstemmed Translation control in apoptosis
title_sort translation control in apoptosis
publisher Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
publishDate 2012
topic_facet Reviews
url http://dspace.nbuv.gov.ua/handle/123456789/139050
citation_txt Translation control in apoptosis / U. Liwak, M.D. Faye, M. Holcik // Experimental Oncology. — 2012. — Т. 34, № 3. — С. 218-230. — Бібліогр.: 123 назв. — англ.
series Experimental Oncology
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AT fayemd translationcontrolinapoptosis
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first_indexed 2023-10-18T21:19:34Z
last_indexed 2023-10-18T21:19:34Z
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