Role of components of microRNA machinery in carcinogenesis
MicroRNAs (miRNAs) are a broad class of non-coding RNAs nearly 21 nucleotides length, which play crucial functions in posttranscriptional gene regulation. These molecules are associated with many developmental and cellular processes in eukaryotic organisms. Current investigation has reported major f...
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| Дата: | 2018 |
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| Автори: | , , |
| Формат: | Стаття |
| Мова: | English |
| Опубліковано: |
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
2018
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| Назва видання: | Experimental Oncology |
| Теми: | |
| Онлайн доступ: | http://dspace.nbuv.gov.ua/handle/123456789/139254 |
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| Назва журналу: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Цитувати: | Role of components of microRNA machinery in carcinogenesis / R. Kian, S. Moradi, S. Ghorbian // Experimental Oncology. — 2018 — Т. 40, № 1. — С. 2–9. — Бібліогр.: 97 назв. — англ. |
Репозитарії
Digital Library of Periodicals of National Academy of Sciences of Ukraine| id |
irk-123456789-139254 |
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dspace |
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irk-123456789-1392542018-06-20T03:06:45Z Role of components of microRNA machinery in carcinogenesis Kian, R. Moradi, S. Ghorbian, S. Reviews MicroRNAs (miRNAs) are a broad class of non-coding RNAs nearly 21 nucleotides length, which play crucial functions in posttranscriptional gene regulation. These molecules are associated with many developmental and cellular processes in eukaryotic organisms. Current investigation has reported major factors contributing to miRNA biogenesis and has constituted basic principles of miRNA function. More recently, it was confirmed that various miRNAs are clearly implicated in human malignancies, such as lung, breast, ovarian, bladder, colon cancer and other kinds of carcinoma. In addition, dysregulation in the miRNA machinery elements such as Dicer, Drosha, DGCR8, Argonaut, and TRBP could be involved in the progress of many tumor types. The purpose of the current review was to compile growing information besides how miRNA biogenesis and gene silencing are modified to develop cancer. 2018 Article Role of components of microRNA machinery in carcinogenesis / R. Kian, S. Moradi, S. Ghorbian // Experimental Oncology. — 2018 — Т. 40, № 1. — С. 2–9. — Бібліогр.: 97 назв. — англ. 1812-9269 http://dspace.nbuv.gov.ua/handle/123456789/139254 en Experimental Oncology Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України |
| institution |
Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| collection |
DSpace DC |
| language |
English |
| topic |
Reviews Reviews |
| spellingShingle |
Reviews Reviews Kian, R. Moradi, S. Ghorbian, S. Role of components of microRNA machinery in carcinogenesis Experimental Oncology |
| description |
MicroRNAs (miRNAs) are a broad class of non-coding RNAs nearly 21 nucleotides length, which play crucial functions in posttranscriptional gene regulation. These molecules are associated with many developmental and cellular processes in eukaryotic organisms. Current investigation has reported major factors contributing to miRNA biogenesis and has constituted basic principles of miRNA function. More recently, it was confirmed that various miRNAs are clearly implicated in human malignancies, such as lung, breast, ovarian, bladder, colon cancer and other kinds of carcinoma. In addition, dysregulation in the miRNA machinery elements such as Dicer, Drosha, DGCR8, Argonaut, and TRBP could be involved in the progress of many tumor types. The purpose of the current review was to compile growing information besides how miRNA biogenesis and gene silencing are modified to develop cancer. |
| format |
Article |
| author |
Kian, R. Moradi, S. Ghorbian, S. |
| author_facet |
Kian, R. Moradi, S. Ghorbian, S. |
| author_sort |
Kian, R. |
| title |
Role of components of microRNA machinery in carcinogenesis |
| title_short |
Role of components of microRNA machinery in carcinogenesis |
| title_full |
Role of components of microRNA machinery in carcinogenesis |
| title_fullStr |
Role of components of microRNA machinery in carcinogenesis |
| title_full_unstemmed |
Role of components of microRNA machinery in carcinogenesis |
| title_sort |
role of components of microrna machinery in carcinogenesis |
| publisher |
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України |
| publishDate |
2018 |
| topic_facet |
Reviews |
| url |
http://dspace.nbuv.gov.ua/handle/123456789/139254 |
| citation_txt |
Role of components of microRNA machinery in carcinogenesis / R. Kian, S. Moradi, S. Ghorbian // Experimental Oncology. — 2018 — Т. 40, № 1. — С. 2–9. — Бібліогр.: 97 назв. — англ. |
| series |
Experimental Oncology |
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AT kianr roleofcomponentsofmicrornamachineryincarcinogenesis AT moradis roleofcomponentsofmicrornamachineryincarcinogenesis AT ghorbians roleofcomponentsofmicrornamachineryincarcinogenesis |
| first_indexed |
2023-10-18T21:19:24Z |
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2023-10-18T21:19:24Z |
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1796152507075919872 |