Theoretical ground for adsorptive therapy of anthracyclines cardiotoxicity
Anthracyclines play an important role in treatment of variety types of cancer due to their high effectiveness and broad spectrum of activity. However, a major limitation of their use is the dose-limiting cardiotoxicity. The inability to predict and prevent anthracycline cardiotoxicity is in part due...
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| Дата: | 2012 |
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| Автори: | , , , |
| Формат: | Стаття |
| Мова: | English |
| Опубліковано: |
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
2012
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| Назва видання: | Experimental Oncology |
| Теми: | |
| Онлайн доступ: | http://dspace.nbuv.gov.ua/handle/123456789/139865 |
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| Назва журналу: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Цитувати: | Theoretical ground for adsorptive therapy of anthracyclines cardiotoxicity / O.O. Shevchuk, E.A. Posokhova, L.A. Sakhno, V.G. Nikolaev // Experimental Oncology. — 2012. — Т. 34, № 4. — С. 314-322. — Бібліогр.: 132 назв. — англ. |
Репозитарії
Digital Library of Periodicals of National Academy of Sciences of Ukraine| id |
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irk-123456789-1398652018-06-22T03:06:08Z Theoretical ground for adsorptive therapy of anthracyclines cardiotoxicity Shevchuk, O.O. Posokhova, E.A. Sakhno, L.A. Nikolaev, V.G. Reviews Anthracyclines play an important role in treatment of variety types of cancer due to their high effectiveness and broad spectrum of activity. However, a major limitation of their use is the dose-limiting cardiotoxicity. The inability to predict and prevent anthracycline cardiotoxicity is in part due to the fact that the molecular and cellular mechanisms remain controversial and incompletely understood. This review focuses on the biochemical basis of the anthracyclines toxic cardiac effects and pharmacological measures to their treatment and preventing. We describe the theoretical substantiation of the enterosorption abilities for diminishing of cardiac damage. 2012 Article Theoretical ground for adsorptive therapy of anthracyclines cardiotoxicity / O.O. Shevchuk, E.A. Posokhova, L.A. Sakhno, V.G. Nikolaev // Experimental Oncology. — 2012. — Т. 34, № 4. — С. 314-322. — Бібліогр.: 132 назв. — англ. 1812-9269 http://dspace.nbuv.gov.ua/handle/123456789/139865 en Experimental Oncology Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України |
| institution |
Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| collection |
DSpace DC |
| language |
English |
| topic |
Reviews Reviews |
| spellingShingle |
Reviews Reviews Shevchuk, O.O. Posokhova, E.A. Sakhno, L.A. Nikolaev, V.G. Theoretical ground for adsorptive therapy of anthracyclines cardiotoxicity Experimental Oncology |
| description |
Anthracyclines play an important role in treatment of variety types of cancer due to their high effectiveness and broad spectrum of activity. However, a major limitation of their use is the dose-limiting cardiotoxicity. The inability to predict and prevent anthracycline cardiotoxicity is in part due to the fact that the molecular and cellular mechanisms remain controversial and incompletely understood. This review focuses on the biochemical basis of the anthracyclines toxic cardiac effects and pharmacological measures to their treatment and preventing. We describe the theoretical substantiation of the enterosorption abilities for diminishing of cardiac damage. |
| format |
Article |
| author |
Shevchuk, O.O. Posokhova, E.A. Sakhno, L.A. Nikolaev, V.G. |
| author_facet |
Shevchuk, O.O. Posokhova, E.A. Sakhno, L.A. Nikolaev, V.G. |
| author_sort |
Shevchuk, O.O. |
| title |
Theoretical ground for adsorptive therapy of anthracyclines cardiotoxicity |
| title_short |
Theoretical ground for adsorptive therapy of anthracyclines cardiotoxicity |
| title_full |
Theoretical ground for adsorptive therapy of anthracyclines cardiotoxicity |
| title_fullStr |
Theoretical ground for adsorptive therapy of anthracyclines cardiotoxicity |
| title_full_unstemmed |
Theoretical ground for adsorptive therapy of anthracyclines cardiotoxicity |
| title_sort |
theoretical ground for adsorptive therapy of anthracyclines cardiotoxicity |
| publisher |
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України |
| publishDate |
2012 |
| topic_facet |
Reviews |
| url |
http://dspace.nbuv.gov.ua/handle/123456789/139865 |
| citation_txt |
Theoretical ground for adsorptive therapy of anthracyclines cardiotoxicity / O.O. Shevchuk, E.A. Posokhova, L.A. Sakhno, V.G. Nikolaev // Experimental Oncology. — 2012. — Т. 34, № 4. — С. 314-322. — Бібліогр.: 132 назв. — англ. |
| series |
Experimental Oncology |
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2023-10-18T21:20:32Z |
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2023-10-18T21:20:32Z |
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