Impact of a tobacco smoke on a metabolism of an organ culture of bovine lenses and potential protection by antioxidants
Smoke from cigarette smoking (CS) has been proposed to be a major environmental risk factor for a variety of human diseases and was implicated also in cataract, an eye lens pacification, which is a major cause of blindness. We have undertaken a study to investigate the eff...
Збережено в:
| Дата: | 2013 |
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| Автори: | , |
| Формат: | Стаття |
| Мова: | English |
| Опубліковано: |
Фізико-хімічний інститут ім. О.В. Богатського НАН України
2013
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| Назва видання: | Актуальні проблеми транспортної медицини |
| Теми: | |
| Онлайн доступ: | http://dspace.nbuv.gov.ua/handle/123456789/140194 |
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| Назва журналу: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Цитувати: | Impact of a tobacco smoke on a metabolism of an organ culture of bovine lenses and potential protection by antioxidants / E. Bormusov, A.Z. Reznick // Актуальні проблеми транспортної медицини. — 2013. — № 4 (34). — С. 105-118. — Бібліогр.: 28 назв. — англ. |
Репозитарії
Digital Library of Periodicals of National Academy of Sciences of Ukraine| Резюме: | Smoke from cigarette smoking (CS) has been proposed to be a major
environmental risk factor for a variety of human diseases and was implicated also in
cataract, an eye lens pacification, which is a major cause of blindness. We have undertaken
a study to investigate the effect of smoke on the physiological integrity and metabolism of
organ cultured lenses. Lenses in organ culture
are metabolically active and have functional
defense systems, thus they pr
ovide an appropriate model for studying the effects of smoke.
Also possible protective action of N-acetyl
L-cysteine (NAC) which is a precursor of
glutathione and the iron chelator Deferoxamine (DFO), was estimated as potential protective
agents against cataract. |
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