Antibodies against benzo

Antibodies against benzo

Aim: To evaluate the production of antibodies against benzo[a]pyrene (BF) (Ab1) and corresponding antiidiotypic antibodies (AM) in mice after immunization with BP-protein conjugate and in lung cancer patients. Materials and Methods: The Ab1 and AM levels were measured by non-competitive ELISA in blo...

Повний опис

Збережено в:
Бібліографічні деталі
Дата:2013
Автори: Ustinov, V.A., Matveeva, V.A., Kostyanko, M.A., Glushkov, A.N.
Формат: Стаття
Мова:English
Опубліковано: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2013
Назва видання:Experimental Oncology
Теми:
Original contributions
Онлайн доступ:http://dspace.nbuv.gov.ua/handle/123456789/145239
Теги: Додати тег
Немає тегів, Будьте першим, хто поставить тег для цього запису!
Назва журналу:Digital Library of Periodicals of National Academy of Sciences of Ukraine
Цитувати:Antibodies against benzo / V.A. Ustinov, V.A. Matveeva, M.A. Kostyanko, A.N. Glushkov // Experimental Oncology. — 2013. — Т. 35, № 3. — С. 207-210. — Бібліогр.: 16 назв. — англ.

Репозитарії

Digital Library of Periodicals of National Academy of Sciences of Ukraine
id irk-123456789-145239
record_format dspace
spelling irk-123456789-1452392019-01-20T01:23:26Z Antibodies against benzo Ustinov, V.A. Matveeva, V.A. Kostyanko, M.A. Glushkov, A.N. Original contributions Aim: To evaluate the production of antibodies against benzo[a]pyrene (BF) (Ab1) and corresponding antiidiotypic antibodies (AM) in mice after immunization with BP-protein conjugate and in lung cancer patients. Materials and Methods: The Ab1 and AM levels were measured by non-competitive ELISA in blood serum of 10 mice immunized with BP-protein conjugate, and in blood serum of 288 healthy persons and 165 lung cancer patients. Results: The Ab] level of was 2-fold higher than Ab2 level in blood serum of BP-immunized mice. In lung cancer patients the Ab1 level was almost 3 times higher and the Ab2 level was by 30% higher than these indexes in healthy individuals. The Ab1/Ab2 ratio was 2 in BP-immunized mice and healthy individuals and l in lung cancer patients. Conclusion: Our data have shown that the Ab1/Ab2 ratio in lung cancer patients differ from that in healthy individuals and is close to the Ab1/Ab2 ratio in BP-immunized mouse. Key Words: benzo[a]pyrene, antibodies, lung cancer. 2013 Article Antibodies against benzo / V.A. Ustinov, V.A. Matveeva, M.A. Kostyanko, A.N. Glushkov // Experimental Oncology. — 2013. — Т. 35, № 3. — С. 207-210. — Бібліогр.: 16 назв. — англ. 1812-9269 http://dspace.nbuv.gov.ua/handle/123456789/145239 en Experimental Oncology Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
institution Digital Library of Periodicals of National Academy of Sciences of Ukraine
collection DSpace DC
language English
topic Original contributions
Original contributions
spellingShingle Original contributions
Original contributions
Ustinov, V.A.
Matveeva, V.A.
Kostyanko, M.A.
Glushkov, A.N.
Antibodies against benzo
Experimental Oncology
description Aim: To evaluate the production of antibodies against benzo[a]pyrene (BF) (Ab1) and corresponding antiidiotypic antibodies (AM) in mice after immunization with BP-protein conjugate and in lung cancer patients. Materials and Methods: The Ab1 and AM levels were measured by non-competitive ELISA in blood serum of 10 mice immunized with BP-protein conjugate, and in blood serum of 288 healthy persons and 165 lung cancer patients. Results: The Ab] level of was 2-fold higher than Ab2 level in blood serum of BP-immunized mice. In lung cancer patients the Ab1 level was almost 3 times higher and the Ab2 level was by 30% higher than these indexes in healthy individuals. The Ab1/Ab2 ratio was 2 in BP-immunized mice and healthy individuals and l in lung cancer patients. Conclusion: Our data have shown that the Ab1/Ab2 ratio in lung cancer patients differ from that in healthy individuals and is close to the Ab1/Ab2 ratio in BP-immunized mouse. Key Words: benzo[a]pyrene, antibodies, lung cancer.
format Article
author Ustinov, V.A.
Matveeva, V.A.
Kostyanko, M.A.
Glushkov, A.N.
author_facet Ustinov, V.A.
Matveeva, V.A.
Kostyanko, M.A.
Glushkov, A.N.
author_sort Ustinov, V.A.
title Antibodies against benzo
title_short Antibodies against benzo
title_full Antibodies against benzo
title_fullStr Antibodies against benzo
title_full_unstemmed Antibodies against benzo
title_sort antibodies against benzo
publisher Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
publishDate 2013
topic_facet Original contributions
url http://dspace.nbuv.gov.ua/handle/123456789/145239
citation_txt Antibodies against benzo / V.A. Ustinov, V.A. Matveeva, M.A. Kostyanko, A.N. Glushkov // Experimental Oncology. — 2013. — Т. 35, № 3. — С. 207-210. — Бібліогр.: 16 назв. — англ.
series Experimental Oncology
work_keys_str_mv AT ustinovva antibodiesagainstbenzo
AT matveevava antibodiesagainstbenzo
AT kostyankoma antibodiesagainstbenzo
AT glushkovan antibodiesagainstbenzo
first_indexed 2023-05-20T17:21:37Z
last_indexed 2023-05-20T17:21:37Z
_version_ 1796153117931208704

Схожі ресурси