Management of non-inflammatory locally advanced breast cancer: focus on surgical approaches
In non-inflammatory locally advanced breast cancer, treatment typically includes neoadjuvant chemotherapy, surgery, and radiation therapy. Neoadjuvant chemotherapy allows in vivo assessment of primary tumor response to chemotherapy and is achieved the early control of micrometastatic disease. It als...
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| Видавець: | Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України |
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| Дата: | 2013 |
| Автори: | , |
| Формат: | Стаття |
| Мова: | English |
| Опубліковано: |
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
2013
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| Назва видання: | Experimental Oncology |
| Теми: | |
| Онлайн доступ: | http://dspace.nbuv.gov.ua/handle/123456789/145260 |
| Теги: |
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| Цитувати: | Management of non-inflammatory locally advanced breast cancer: focus on surgical approaches / A. Eroğlu, F. Aydin // Experimental Oncology. — 2013. — Т. 35, № 4. — С. 272-279. — Бібліогр.: 44 назв. — англ. |
Репозиторії
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irk-123456789-1452602019-01-21T01:23:48Z Management of non-inflammatory locally advanced breast cancer: focus on surgical approaches Eroğlu, A. Aydin, F. Special issue on breast cancer In non-inflammatory locally advanced breast cancer, treatment typically includes neoadjuvant chemotherapy, surgery, and radiation therapy. Neoadjuvant chemotherapy allows in vivo assessment of primary tumor response to chemotherapy and is achieved the early control of micrometastatic disease. It also significantly improves surgical outcomes. Patients achieving pathologic complete response after neoadjuvant chemotherapy have a better survival. Tumor downsizing can make breast conserving therapy by allowing for smaller resections and improving cosmesis. Tumor downstaging with chemotherapy can allow breast conserving surgery in patients who are initially candidate for mastectomy. Sentinel lymph node biopsy is an appropriate alternative to routine staging axillary dissection for early-stage breast cancer patients with clinically negative axillary nodes. During the last years there have been a number of clinical studies on effectiveness and role of sentinel lymph node biopsy in patients receiving neoadjuvant chemotherapy. The use of sentinel lymph node biopsy is an alternative approach to axillary dissection in patients with neoadjuvant therapy. In conclusion, patients with locally advanced breast cancer are treated with neoadjuvant chemotherapy followed by breast conserving surgery with axillary dissection and radiation therapy as a part of the multimodality management. 2013 Article Management of non-inflammatory locally advanced breast cancer: focus on surgical approaches / A. Eroğlu, F. Aydin // Experimental Oncology. — 2013. — Т. 35, № 4. — С. 272-279. — Бібліогр.: 44 назв. — англ. 1812-9269 http://dspace.nbuv.gov.ua/handle/123456789/145260 en Experimental Oncology Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України |
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Digital Library of Periodicals of National Academy of Sciences of Ukraine |
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DSpace DC |
| language |
English |
| topic |
Special issue on breast cancer Special issue on breast cancer |
| spellingShingle |
Special issue on breast cancer Special issue on breast cancer Eroğlu, A. Aydin, F. Management of non-inflammatory locally advanced breast cancer: focus on surgical approaches Experimental Oncology |
| description |
In non-inflammatory locally advanced breast cancer, treatment typically includes neoadjuvant chemotherapy, surgery, and radiation therapy. Neoadjuvant chemotherapy allows in vivo assessment of primary tumor response to chemotherapy and is achieved the early control of micrometastatic disease. It also significantly improves surgical outcomes. Patients achieving pathologic complete response after neoadjuvant chemotherapy have a better survival. Tumor downsizing can make breast conserving therapy by allowing for smaller resections and improving cosmesis. Tumor downstaging with chemotherapy can allow breast conserving surgery in patients who are initially candidate for mastectomy. Sentinel lymph node biopsy is an appropriate alternative to routine staging axillary dissection for early-stage breast cancer patients with clinically negative axillary nodes. During the last years there have been a number of clinical studies on effectiveness and role of sentinel lymph node biopsy in patients receiving neoadjuvant chemotherapy. The use of sentinel lymph node biopsy is an alternative approach to axillary dissection in patients with neoadjuvant therapy. In conclusion, patients with locally advanced breast cancer are treated with neoadjuvant chemotherapy followed by breast conserving surgery with axillary dissection and radiation therapy as a part of the multimodality management. |
| format |
Article |
| author |
Eroğlu, A. Aydin, F. |
| author_facet |
Eroğlu, A. Aydin, F. |
| author_sort |
Eroğlu, A. |
| title |
Management of non-inflammatory locally advanced breast cancer: focus on surgical approaches |
| title_short |
Management of non-inflammatory locally advanced breast cancer: focus on surgical approaches |
| title_full |
Management of non-inflammatory locally advanced breast cancer: focus on surgical approaches |
| title_fullStr |
Management of non-inflammatory locally advanced breast cancer: focus on surgical approaches |
| title_full_unstemmed |
Management of non-inflammatory locally advanced breast cancer: focus on surgical approaches |
| title_sort |
management of non-inflammatory locally advanced breast cancer: focus on surgical approaches |
| publisher |
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України |
| publishDate |
2013 |
| topic_facet |
Special issue on breast cancer |
| url |
http://dspace.nbuv.gov.ua/handle/123456789/145260 |
| citation_txt |
Management of non-inflammatory locally advanced breast cancer: focus on surgical approaches / A. Eroğlu, F. Aydin // Experimental Oncology. — 2013. — Т. 35, № 4. — С. 272-279. — Бібліогр.: 44 назв. — англ. |
| series |
Experimental Oncology |
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2023-05-20T17:21:39Z |
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2023-05-20T17:21:39Z |
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