Receptor status of tumor as prognostic factor in patients with bilateral breast cancer
Aim: To determine the receptor status of tumors as prognostic factor in development of bilateral breast cancer (BBC) and factor of prognosis of disease. Patients and Methods: 272 cases of BBC during the period from 1995 to 2011 in different oncological institutions of Ukraine have been analyzed. Res...
Збережено в:
| Дата: | 2013 |
|---|---|
| Автори: | , , |
| Формат: | Стаття |
| Мова: | English |
| Опубліковано: |
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
2013
|
| Назва видання: | Experimental Oncology |
| Теми: | |
| Онлайн доступ: | http://dspace.nbuv.gov.ua/handle/123456789/145263 |
| Теги: |
Додати тег
Немає тегів, Будьте першим, хто поставить тег для цього запису!
|
| Назва журналу: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Цитувати: | Receptor status of tumor as prognostic factor in patients with bilateral breast cancer / D.Y. Tsyhyka, Y.S. Hotko, O.T. Devinyak // Experimental Oncology. — 2013. — Т. 35, № 4. — С. 291-294. — Бібліогр.: 11 назв. — англ. |
Репозитарії
Digital Library of Periodicals of National Academy of Sciences of Ukraine| id |
irk-123456789-145263 |
|---|---|
| record_format |
dspace |
| spelling |
irk-123456789-1452632019-01-21T01:23:01Z Receptor status of tumor as prognostic factor in patients with bilateral breast cancer Tsyhyka, D.Y. Hotko, Y.S. Devinyak, O.T. Special issue on breast cancer Aim: To determine the receptor status of tumors as prognostic factor in development of bilateral breast cancer (BBC) and factor of prognosis of disease. Patients and Methods: 272 cases of BBC during the period from 1995 to 2011 in different oncological institutions of Ukraine have been analyzed. Results: Patients with metachronous BBC with positive status of hormone receptors (HR) of tumors have significantly better indices of overall and progression-free survival (three-years — 95%, five-years — 72%), than patients with HR-negative status (among them nobody has survived over 5 years). In patients with synchronous BBC, the receptor status of tumors has similar influence on the prognosis of survival. Nevertheless, indices of overall survival (65%) and progression-free survival (66%) in HR-positive patients were lower than that at metachronous BBC (overall survival and progression-free survival — 72%). Conclusions: Synchronous breast cancer has more aggressive clinical course than metachronous one. It was determined significant influence of receptor status of tumors on the overall survival and progression-free survival in patients with BBC. 2013 Article Receptor status of tumor as prognostic factor in patients with bilateral breast cancer / D.Y. Tsyhyka, Y.S. Hotko, O.T. Devinyak // Experimental Oncology. — 2013. — Т. 35, № 4. — С. 291-294. — Бібліогр.: 11 назв. — англ. 1812-9269 http://dspace.nbuv.gov.ua/handle/123456789/145263 en Experimental Oncology Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України |
| institution |
Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| collection |
DSpace DC |
| language |
English |
| topic |
Special issue on breast cancer Special issue on breast cancer |
| spellingShingle |
Special issue on breast cancer Special issue on breast cancer Tsyhyka, D.Y. Hotko, Y.S. Devinyak, O.T. Receptor status of tumor as prognostic factor in patients with bilateral breast cancer Experimental Oncology |
| description |
Aim: To determine the receptor status of tumors as prognostic factor in development of bilateral breast cancer (BBC) and factor of prognosis of disease. Patients and Methods: 272 cases of BBC during the period from 1995 to 2011 in different oncological institutions of Ukraine have been analyzed. Results: Patients with metachronous BBC with positive status of hormone receptors (HR) of tumors have significantly better indices of overall and progression-free survival (three-years — 95%, five-years — 72%), than patients with HR-negative status (among them nobody has survived over 5 years). In patients with synchronous BBC, the receptor status of tumors has similar influence on the prognosis of survival. Nevertheless, indices of overall survival (65%) and progression-free survival (66%) in HR-positive patients were lower than that at metachronous BBC (overall survival and progression-free survival — 72%). Conclusions: Synchronous breast cancer has more aggressive clinical course than metachronous one. It was determined significant influence of receptor status of tumors on the overall survival and progression-free survival in patients with BBC. |
| format |
Article |
| author |
Tsyhyka, D.Y. Hotko, Y.S. Devinyak, O.T. |
| author_facet |
Tsyhyka, D.Y. Hotko, Y.S. Devinyak, O.T. |
| author_sort |
Tsyhyka, D.Y. |
| title |
Receptor status of tumor as prognostic factor in patients with bilateral breast cancer |
| title_short |
Receptor status of tumor as prognostic factor in patients with bilateral breast cancer |
| title_full |
Receptor status of tumor as prognostic factor in patients with bilateral breast cancer |
| title_fullStr |
Receptor status of tumor as prognostic factor in patients with bilateral breast cancer |
| title_full_unstemmed |
Receptor status of tumor as prognostic factor in patients with bilateral breast cancer |
| title_sort |
receptor status of tumor as prognostic factor in patients with bilateral breast cancer |
| publisher |
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України |
| publishDate |
2013 |
| topic_facet |
Special issue on breast cancer |
| url |
http://dspace.nbuv.gov.ua/handle/123456789/145263 |
| citation_txt |
Receptor status of tumor as prognostic factor in patients with bilateral breast cancer / D.Y. Tsyhyka, Y.S. Hotko, O.T. Devinyak // Experimental Oncology. — 2013. — Т. 35, № 4. — С. 291-294. — Бібліогр.: 11 назв. — англ. |
| series |
Experimental Oncology |
| work_keys_str_mv |
AT tsyhykady receptorstatusoftumorasprognosticfactorinpatientswithbilateralbreastcancer AT hotkoys receptorstatusoftumorasprognosticfactorinpatientswithbilateralbreastcancer AT devinyakot receptorstatusoftumorasprognosticfactorinpatientswithbilateralbreastcancer |
| first_indexed |
2023-05-20T17:21:40Z |
| last_indexed |
2023-05-20T17:21:40Z |
| _version_ |
1796153124351639552 |