Human papilloma virus and nasopharyngeal carcinoma: pathology, prognosis, recurrence and mortality of the disease
Background: One of the malignant tumors among head and neck cancers is nasopharyngeal carcinoma. Many studies consider human papilloma virus (HPV) as a cause for nasopharyngeal carcinoma. Methods: 41 paraffin-wax-embedded block samples were examined to detect HPV DNA and its subtype’s presence by po...
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| Дата: | 2014 |
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| Автори: | , , , , , , |
| Формат: | Стаття |
| Мова: | English |
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Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
2014
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| Назва видання: | Experimental Oncology |
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| Онлайн доступ: | http://dspace.nbuv.gov.ua/handle/123456789/145370 |
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| Назва журналу: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Цитувати: | Human papilloma virus and nasopharyngeal carcinoma: pathology, prognosis, recurrence and mortality of the disease / S. Atighechi, M.R. Ahmadpour Baghdadabad, S.A. Mirvakili, M.H. Sheikhha, M.H. Baradaranfar, M.H. Dadgarnia, N. Behniafard // Experimental Oncology. — 2014. — Т. 36, № 3. — С. 215-216. — Бібліогр.: 12 назв. — англ. |
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irk-123456789-1453702019-01-22T01:23:22Z Human papilloma virus and nasopharyngeal carcinoma: pathology, prognosis, recurrence and mortality of the disease Atighechi, S. Mirvakili, S.A. Sheikhha, M.H. Baradaranfar, M.H. Dadgarnia, M.H. Behniafard, N. Ahmadpour Baghdadabad, M.R. Short communications Background: One of the malignant tumors among head and neck cancers is nasopharyngeal carcinoma. Many studies consider human papilloma virus (HPV) as a cause for nasopharyngeal carcinoma. Methods: 41 paraffin-wax-embedded block samples were examined to detect HPV DNA and its subtype’s presence by polymerase chain reaction. The recurrence, prognosis and survival were evaluated for an average of 48 months. Results: HPV DNA was positive in 9 patients (22%). The overall recurrence rate was 75% in HPV negative patients and 11% in HPV positive ones. The mortality rate in HPV negative and positive patients was 37.5% and 0%, respectively. Conclusion: HPV type 18 and 16 were the most common subtypes. Also, it can be implied that patients which are HPV positive had better prognosis and also less recurrence. Key Words: human papilloma virus, nasopharyngeal cancer, polymerase chain reaction, prognosis, recurrence. 2014 Article Human papilloma virus and nasopharyngeal carcinoma: pathology, prognosis, recurrence and mortality of the disease / S. Atighechi, M.R. Ahmadpour Baghdadabad, S.A. Mirvakili, M.H. Sheikhha, M.H. Baradaranfar, M.H. Dadgarnia, N. Behniafard // Experimental Oncology. — 2014. — Т. 36, № 3. — С. 215-216. — Бібліогр.: 12 назв. — англ. 1812-9269 http://dspace.nbuv.gov.ua/handle/123456789/145370 en Experimental Oncology Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України |
| institution |
Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| collection |
DSpace DC |
| language |
English |
| topic |
Short communications Short communications |
| spellingShingle |
Short communications Short communications Atighechi, S. Mirvakili, S.A. Sheikhha, M.H. Baradaranfar, M.H. Dadgarnia, M.H. Behniafard, N. Ahmadpour Baghdadabad, M.R. Human papilloma virus and nasopharyngeal carcinoma: pathology, prognosis, recurrence and mortality of the disease Experimental Oncology |
| description |
Background: One of the malignant tumors among head and neck cancers is nasopharyngeal carcinoma. Many studies consider human papilloma virus (HPV) as a cause for nasopharyngeal carcinoma. Methods: 41 paraffin-wax-embedded block samples were examined to detect HPV DNA and its subtype’s presence by polymerase chain reaction. The recurrence, prognosis and survival were evaluated for an average of 48 months. Results: HPV DNA was positive in 9 patients (22%). The overall recurrence rate was 75% in HPV negative patients and 11% in HPV positive ones. The mortality rate in HPV negative and positive patients was 37.5% and 0%, respectively. Conclusion: HPV type 18 and 16 were the most common subtypes. Also, it can be implied that patients which are HPV positive had better prognosis and also less recurrence. Key Words: human papilloma virus, nasopharyngeal cancer, polymerase chain reaction, prognosis, recurrence. |
| format |
Article |
| author |
Atighechi, S. Mirvakili, S.A. Sheikhha, M.H. Baradaranfar, M.H. Dadgarnia, M.H. Behniafard, N. Ahmadpour Baghdadabad, M.R. |
| author_facet |
Atighechi, S. Mirvakili, S.A. Sheikhha, M.H. Baradaranfar, M.H. Dadgarnia, M.H. Behniafard, N. Ahmadpour Baghdadabad, M.R. |
| author_sort |
Atighechi, S. |
| title |
Human papilloma virus and nasopharyngeal carcinoma: pathology, prognosis, recurrence and mortality of the disease |
| title_short |
Human papilloma virus and nasopharyngeal carcinoma: pathology, prognosis, recurrence and mortality of the disease |
| title_full |
Human papilloma virus and nasopharyngeal carcinoma: pathology, prognosis, recurrence and mortality of the disease |
| title_fullStr |
Human papilloma virus and nasopharyngeal carcinoma: pathology, prognosis, recurrence and mortality of the disease |
| title_full_unstemmed |
Human papilloma virus and nasopharyngeal carcinoma: pathology, prognosis, recurrence and mortality of the disease |
| title_sort |
human papilloma virus and nasopharyngeal carcinoma: pathology, prognosis, recurrence and mortality of the disease |
| publisher |
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України |
| publishDate |
2014 |
| topic_facet |
Short communications |
| url |
http://dspace.nbuv.gov.ua/handle/123456789/145370 |
| citation_txt |
Human papilloma virus and nasopharyngeal carcinoma: pathology, prognosis, recurrence and mortality of the disease / S. Atighechi, M.R. Ahmadpour Baghdadabad, S.A. Mirvakili, M.H. Sheikhha, M.H. Baradaranfar, M.H. Dadgarnia, N. Behniafard // Experimental Oncology. — 2014. — Т. 36, № 3. — С. 215-216. — Бібліогр.: 12 назв. — англ. |
| series |
Experimental Oncology |
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2023-05-20T17:21:58Z |
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2023-05-20T17:21:58Z |
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