Precision therapy to target apoptosis in prostate cancer
Androgen-independent prostate cancer shows limited response to existing systemic therapies. Recent advances in prostate-selective targeting of small molecule inhibitors and bacterial toxins have created opportunities to design a new generation of therapies for advanced prostate cancer. Yet prioritiz...
Збережено в:
| Дата: | 2014 |
|---|---|
| Автор: | |
| Формат: | Стаття |
| Мова: | English |
| Опубліковано: |
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
2014
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| Назва видання: | Experimental Oncology |
| Теми: | |
| Онлайн доступ: | http://dspace.nbuv.gov.ua/handle/123456789/145372 |
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| Назва журналу: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Цитувати: | Precision therapy to target apoptosis in prostate cancer / G. Kulik // Experimental Oncology. — 2014. — Т. 36, № 4. — С. 226-230. — Бібліогр.: 48 назв. — англ. |
Репозитарії
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irk-123456789-1453722019-01-22T01:23:25Z Precision therapy to target apoptosis in prostate cancer Kulik, G. Reviews Androgen-independent prostate cancer shows limited response to existing systemic therapies. Recent advances in prostate-selective targeting of small molecule inhibitors and bacterial toxins have created opportunities to design a new generation of therapies for advanced prostate cancer. Yet prioritizing targets for these therapies remain challenging, since multiple mechanisms contribute to the pathophysiology of androgen-independent prostate cancer. This review explores the possibility of targeting the apoptosis regulatory network as most direct approach to efficient treatment of advanced androgen-independent prostate cancer. Key Words: prostate cancer, apoptosis, prostate-selective therapies, PSA-activated pro-drugs, PSMA-targeting toxins. 2014 Article Precision therapy to target apoptosis in prostate cancer / G. Kulik // Experimental Oncology. — 2014. — Т. 36, № 4. — С. 226-230. — Бібліогр.: 48 назв. — англ. 1812-9269 http://dspace.nbuv.gov.ua/handle/123456789/145372 en Experimental Oncology Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України |
| institution |
Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| collection |
DSpace DC |
| language |
English |
| topic |
Reviews Reviews |
| spellingShingle |
Reviews Reviews Kulik, G. Precision therapy to target apoptosis in prostate cancer Experimental Oncology |
| description |
Androgen-independent prostate cancer shows limited response to existing systemic therapies. Recent advances in prostate-selective targeting of small molecule inhibitors and bacterial toxins have created opportunities to design a new generation of therapies for advanced prostate cancer. Yet prioritizing targets for these therapies remain challenging, since multiple mechanisms contribute to the pathophysiology of androgen-independent prostate cancer. This review explores the possibility of targeting the apoptosis regulatory network as most direct approach to efficient treatment of advanced androgen-independent prostate cancer. Key Words: prostate cancer, apoptosis, prostate-selective therapies, PSA-activated pro-drugs, PSMA-targeting toxins. |
| format |
Article |
| author |
Kulik, G. |
| author_facet |
Kulik, G. |
| author_sort |
Kulik, G. |
| title |
Precision therapy to target apoptosis in prostate cancer |
| title_short |
Precision therapy to target apoptosis in prostate cancer |
| title_full |
Precision therapy to target apoptosis in prostate cancer |
| title_fullStr |
Precision therapy to target apoptosis in prostate cancer |
| title_full_unstemmed |
Precision therapy to target apoptosis in prostate cancer |
| title_sort |
precision therapy to target apoptosis in prostate cancer |
| publisher |
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України |
| publishDate |
2014 |
| topic_facet |
Reviews |
| url |
http://dspace.nbuv.gov.ua/handle/123456789/145372 |
| citation_txt |
Precision therapy to target apoptosis in prostate cancer / G. Kulik // Experimental Oncology. — 2014. — Т. 36, № 4. — С. 226-230. — Бібліогр.: 48 назв. — англ. |
| series |
Experimental Oncology |
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AT kulikg precisiontherapytotargetapoptosisinprostatecancer |
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2023-05-20T17:21:59Z |
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2023-05-20T17:21:59Z |
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