Overview on association of different types of leukemias with radiation exposure

Exposure to ionizing radiation is associated with increasing risk of various types of hematological malignancies. The results of major studies on association of leukemias and radiation exposure of large populations in Japan and in Ukraine are analyzed. The patterns of different types of leukemia in...

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Бібліографічні деталі
Дата:2015
Автори: Gluzman, D.F., Sklyarenko, L.M., Zavelevich, M.P., Koval, S.V., Ivanivska, T.S., Rodionova, N.K.
Формат: Стаття
Мова:English
Опубліковано: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2015
Назва видання:Experimental Oncology
Теми:
Онлайн доступ:http://dspace.nbuv.gov.ua/handle/123456789/145461
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Назва журналу:Digital Library of Periodicals of National Academy of Sciences of Ukraine
Цитувати:Overview on association of different types of leukemias with radiation exposure / D.F. Gluzman, L.M. Sklyarenko, M.P. Zavelevich, S.V. Koval, T.S. Ivanivska, N.K. Rodionova // Experimental Oncology. — 2015. — Т. 37, № 2. — С. 89-93. — Бібліогр.: 27 назв. — англ.

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Digital Library of Periodicals of National Academy of Sciences of Ukraine
Опис
Резюме:Exposure to ionizing radiation is associated with increasing risk of various types of hematological malignancies. The results of major studies on association of leukemias and radiation exposure of large populations in Japan and in Ukraine are analyzed. The patterns of different types of leukemia in 295 Chernobyl clean-up workers diagnosed according to the criteria of up-to-date World Health Organization classification within 10–25 years following Chernobyl catastrophe are summarized. In fact, a broad spectrum of radiation-related hematological malignancies has been revealed both in Life Span Study in Japan and in study of Chernobyl clean-up workers in Ukraine. The importance of the precise diagnosis of tumors of hematopoietic and lymphoid tissues according to up-to-date classifications for elucidating the role of radiation as a causative factor of leukemias is emphasized. Such studies are of high importance since according to the recent findings, radiation-associated excess risks of several types of leukemias seem to persist throughout the follow-up period up to 55 years after the radiation exposure. Key Words: ionizing radiation, hematological malignancies, leukemia risk, Chernobyl clean-up workers.