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Effect of dichloroacetate on Lewis lung carcinoma growth and metastasis

Effect of dichloroacetate on Lewis lung carcinoma growth and metastasis

A hallmark of malignancy is excessive tumor glycolysis, even in the presence of oxygen, which causes lactacidosis in the tumor microenvironment and favors tumor cell proliferation and survival. For this reason antimetabolic agents which target tumor cell metabolism are being researched extensively a...

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Bibliographic Details
Main Authors: Kolesnik, D.L., Pyaskovskaya, O.N., Boychuk, I.V., Dasyukevich, O.I., Melnikov, O.R., Tarasov, A.S., Solyanik, G.I.
Format: Article
Language:English
Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2015
Series:Experimental Oncology
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Online Access:http://dspace.nbuv.gov.ua/handle/123456789/145468
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http://dspace.nbuv.gov.ua/handle/123456789/145468

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