Survival rates of familial and sporadic prostate cancer patients
Aim: To compare cancer-specific survival rates for familial and sporadic prostate cancer patients. Materials and Methods: Gleason score and age at diagnosis of familial group and sporadic group were compared by χ² and t-test. Cancer-specific survival rates were analyzed by the Kaplan — Meier method...
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| Дата: | 2015 |
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| Автори: | , , , , , , , |
| Формат: | Стаття |
| Мова: | English |
| Опубліковано: |
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
2015
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| Назва видання: | Experimental Oncology |
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| Онлайн доступ: | http://dspace.nbuv.gov.ua/handle/123456789/145473 |
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| Назва журналу: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Цитувати: | Survival rates of familial and sporadic prostate cancer patients / J. Plonis, M. Nakazawa-Miklasevica, A. Malevskis, P. Vaganovs, S. Pildava, E. Vjaters, J. Gardovskis, E. Miklasevics // Experimental Oncology. — 2015. — Т. 37, № 2. — С. 154-155. — Бібліогр.: 12 назв. — англ. |
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irk-123456789-1454732019-01-23T01:23:27Z Survival rates of familial and sporadic prostate cancer patients Plonis, J. Nakazawa-Miklasevica, M. Malevskis, A. Vaganovs, P. Pildava, S. Vjaters, E. Gardovskis, J. Miklasevics, E. Short communications Aim: To compare cancer-specific survival rates for familial and sporadic prostate cancer patients. Materials and Methods: Gleason score and age at diagnosis of familial group and sporadic group were compared by χ² and t-test. Cancer-specific survival rates were analyzed by the Kaplan — Meier method and compared by log-rank test. Statistically significant level was set at p < 0.05. Results: Among 1175 prostate cancer patients, familial group consisted of 215 (18.3%) patients, the sporadic group consisted of 960 (81.7%) patients. The familial group patient’s mean age at diagnosis (58.9 years old, 95% confidence interval (CI) 57.8–60.1) was significantly younger than that of sporadic group patients (67.2 years old, 95% CI 66.7–67.6) (p < 0.0001). Comparing Gleason score between familial group and sporadic group revealed no statistically significant difference. The analysis showed that 92% (95% CI 0.88–0.97) of familial group patients had a 10-year cancer-specific survival rates, which was a significantly better outcome than that of sporadic group with 69% (95% CI 0.60–0.78) 10-year cancer-specific survival rates (p = 0.0237). Conclusion: The study data demonstrate statistically significant difference between familial group and sporadic group concerning age and cancer-specific survival rates, but not Gleason score. Key Words: prostate cancer, hereditary, familial, survival rates. 2015 Article Survival rates of familial and sporadic prostate cancer patients / J. Plonis, M. Nakazawa-Miklasevica, A. Malevskis, P. Vaganovs, S. Pildava, E. Vjaters, J. Gardovskis, E. Miklasevics // Experimental Oncology. — 2015. — Т. 37, № 2. — С. 154-155. — Бібліогр.: 12 назв. — англ. 1812-9269 http://dspace.nbuv.gov.ua/handle/123456789/145473 en Experimental Oncology Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України |
| institution |
Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| collection |
DSpace DC |
| language |
English |
| topic |
Short communications Short communications |
| spellingShingle |
Short communications Short communications Plonis, J. Nakazawa-Miklasevica, M. Malevskis, A. Vaganovs, P. Pildava, S. Vjaters, E. Gardovskis, J. Miklasevics, E. Survival rates of familial and sporadic prostate cancer patients Experimental Oncology |
| description |
Aim: To compare cancer-specific survival rates for familial and sporadic prostate cancer patients. Materials and Methods: Gleason score and age at diagnosis of familial group and sporadic group were compared by χ² and t-test. Cancer-specific survival rates were analyzed by the Kaplan — Meier method and compared by log-rank test. Statistically significant level was set at p < 0.05. Results: Among 1175 prostate cancer patients, familial group consisted of 215 (18.3%) patients, the sporadic group consisted of 960 (81.7%) patients. The familial group patient’s mean age at diagnosis (58.9 years old, 95% confidence interval (CI) 57.8–60.1) was significantly younger than that of sporadic group patients (67.2 years old, 95% CI 66.7–67.6) (p < 0.0001). Comparing Gleason score between familial group and sporadic group revealed no statistically significant difference. The analysis showed that 92% (95% CI 0.88–0.97) of familial group patients had a 10-year cancer-specific survival rates, which was a significantly better outcome than that of sporadic group with 69% (95% CI 0.60–0.78) 10-year cancer-specific survival rates (p = 0.0237). Conclusion: The study data demonstrate statistically significant difference between familial group and sporadic group concerning age and cancer-specific survival rates, but not Gleason score. Key Words: prostate cancer, hereditary, familial, survival rates. |
| format |
Article |
| author |
Plonis, J. Nakazawa-Miklasevica, M. Malevskis, A. Vaganovs, P. Pildava, S. Vjaters, E. Gardovskis, J. Miklasevics, E. |
| author_facet |
Plonis, J. Nakazawa-Miklasevica, M. Malevskis, A. Vaganovs, P. Pildava, S. Vjaters, E. Gardovskis, J. Miklasevics, E. |
| author_sort |
Plonis, J. |
| title |
Survival rates of familial and sporadic prostate cancer patients |
| title_short |
Survival rates of familial and sporadic prostate cancer patients |
| title_full |
Survival rates of familial and sporadic prostate cancer patients |
| title_fullStr |
Survival rates of familial and sporadic prostate cancer patients |
| title_full_unstemmed |
Survival rates of familial and sporadic prostate cancer patients |
| title_sort |
survival rates of familial and sporadic prostate cancer patients |
| publisher |
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України |
| publishDate |
2015 |
| topic_facet |
Short communications |
| url |
http://dspace.nbuv.gov.ua/handle/123456789/145473 |
| citation_txt |
Survival rates of familial and sporadic prostate cancer patients / J. Plonis, M. Nakazawa-Miklasevica, A. Malevskis, P. Vaganovs, S. Pildava, E. Vjaters, J. Gardovskis, E. Miklasevics // Experimental Oncology. — 2015. — Т. 37, № 2. — С. 154-155. — Бібліогр.: 12 назв. — англ. |
| series |
Experimental Oncology |
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