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Gastric signet-ring cell carcinoma with hypersecretion of β-Human chorionic gonadotropin and review of the literature
β-Human chorionic gonadotropin (β-HCG) is an embryonic protein secreted by the syncytiotrophoblast of the placenta. The determination of the plasma β-HCG level is routinely used for the diagnosis and the follow-up of germ cell tumors. Some adenocarcinomas have been described as being rarely associat...
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Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
2018
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Series: | Experimental Oncology |
Subjects: | |
Online Access: | http://dspace.nbuv.gov.ua/handle/123456789/145591 |
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Summary: | β-Human chorionic gonadotropin (β-HCG) is an embryonic protein secreted by the syncytiotrophoblast of the placenta. The determination of the plasma β-HCG level is routinely used for the diagnosis and the follow-up of germ cell tumors. Some adenocarcinomas have been described as being rarely associated with β-HCG hypersecretion. We report a case of gastric signet-ring cell carcinoma with β-HCG hypersecretion and propose hypotheses to explain the pathogenesis of such hypersecretion. Key Words: β-Human chorionic gonadotropin, gastric signet-ring cell carcinoma. |
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