Vascular Cognitive Impairment with NO Dementia: Neuropsychology, Brain Imaging, and Event-Related Potentials

• Дата: 2013
• Автори: Jiang, B., Yao, G., Yao, C., Zhang, Yu., Ge, J., Qiu, E.
• Формат: Стаття
• Мова: English
• Опубліковано: Інститут фізіології ім. О.О. Богомольця НАН України 2013
• Назва видання: Нейрофизиология
• Онлайн доступ: http://dspace.nbuv.gov.ua/handle/123456789/148125
• Назва журналу: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Цитувати: Vascular Cognitive Impairment with NO Dementia: Neuropsychology, Brain Imaging, and Event-Related Potentials / B. Jiang, G. Yao, C. Yao, Yu. Zhang, J. Ge, E. Qiu // Нейрофизиология. — 2013. — Т. 45, № 4. — С. 362-368. — Бібліогр.: 19 назв. — англ.

We investigated the neuropsychological characteristics, cranial MRI, and P300 ERPs in patients suffering from vascular cognitive impairment with no dementia (VCIND). A study was performed on 68 cases of VCIND after stroke. The cranial MRI patterns and P300 waves of the patients were compared with those of 56 stroke patients without cognitive impairment and 52 healthy subjects. The MoCA (Montreal Cognitive Assessment) was also used to assess their mental status. The proportion of patients with frontotemporal lesions, multiple lesions, and leukoaraiosis (LA) in the VCIND group was greater than that in the stroke group. The cognitive impairment in patients with the former deficiencies was more significant. The MoCA scores in the VCIND group were significantly lower, and the P300 latency was significantly longer, as compared with other two groups. The P300 latency inversely correlated with the MoCA score. Patients with frontotemporal lesions, multiple lesions, and LA are susceptible to cognitive impairment. The MoCA score and the P300 test are helpful for the early diagnosis of VCIND.