Optimal Testing Intervals in the Squatting Test to Determine Baroreflex Sensitivity

The recently introduced “squatting test” (ST) utilizes a simple postural change to perturb the blood pressure and to assess baroreflex sensitivity (BRS). In our study, we estimated the reproducibility of and the optimal testing interval between the STs in healthy volunteers. Thirty-four subjects...

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Бібліографічні деталі
Видавець:Інститут фізіології ім. О.О. Богомольця НАН України
Дата:2014
Автори: Ishitsuka, S., Kusuyama, N., Tanaka, M.
Формат: Стаття
Мова:English
Опубліковано: Інститут фізіології ім. О.О. Богомольця НАН України 2014
Назва видання:Нейрофизиология
Онлайн доступ:http://dspace.nbuv.gov.ua/handle/123456789/148354
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Цитувати:Optimal Testing Intervals in the Squatting Test to Determine Baroreflex Sensitivity / S. Ishitsuka, N. Kusuyama, M. Tanaka // Нейрофизиология. — 2014. — Т. 46, № 6. — С. 559-565. — Бібліогр.: 24 назв. — англ.

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Digital Library of Periodicals of National Academy of Sciences of Ukraine
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Резюме:The recently introduced “squatting test” (ST) utilizes a simple postural change to perturb the blood pressure and to assess baroreflex sensitivity (BRS). In our study, we estimated the reproducibility of and the optimal testing interval between the STs in healthy volunteers. Thirty-four subjects free of cardiovascular disorders and taking no medication were instructed to perform the repeated ST at 30-sec, 1-min, and 3-min intervals in duplicate in a random sequence, while the systolic blood pressure (SBP) and pulse intervals were measured. Baroreflex sensitivity was estimated by plotting reflex increases and decreases in the SBP and succeeding pulse intervals during stand-to-squat and squat-to-stand maneuvers, respectively. Correlations between duplicate BRS data at each testing interval were analyzed by the Pearson’s correlation coefficient, while agreements were assessed by Bland-Altman plots. Two measurements of BRS during stand-to-squat and squat-to-stand maneuvers demonstrated significant correlations at both 1-min and 3-min intervals, while at 30-sec intervals correlation was poor. Correlation coefficients became considerably greater in each maneuver as the measurement interval was increased from 30 sec to 3 min. Our results suggest that the testing interval in the ST should be at least 1 min long, but ideally it should be longer than or equal to 3 min, to assess the baroreflex adequately.