Different types of biotechnological wound coverages created with the application of alive human cells

• Дата: 2015
• Автори: Papuga, A.Ye., Lukash, L.L.
• Формат: Стаття
• Мова: English
• Опубліковано: Інститут молекулярної біології і генетики НАН України 2015
• Назва видання: Вiopolymers and Cell
• Теми: Reviews
• Онлайн доступ: http://dspace.nbuv.gov.ua/handle/123456789/152438
• Назва журналу: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Цитувати: Different types of biotechnological wound coverages created with the application of alive human cells / A.Ye. Papuga, L.L. Lukash // Вiopolymers and Cell. — 2015. — Т. 31, № 2. — С. 83-96. — Бібліогр.: 118 назв. — англ.

Currently, the development and the implementation of the new biotechnological wound coverings (skin equivalents) designed for temporal or permanent replacement of damaged or destroyed areas of human skin remains extremely actual relevant in clinical practice. Skin equivalents or equivalents of individual skin layers which include alive cells of different types take a special place among the artificial wound coverings. They mostly contain two basic types of cells – fibroblasts and keratinocytes (together or separately). Such bioconstructions are usually served as temporary coverings, which supply the damaged skin by biologically active substances and stimulate the regeneration of the patient's own tissues. In this review we consider as commercially available wound coverings and those which are still studied in the laboratories. Until now ideal substitutes of natural skin have not yet created, so the efforts of many researchers are focusing on the solution of this problem.