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Isoforms of elongation factor eEF1A may be differently regulated at post-transcriptional level in breast cancer progression

Isoforms of elongation factor eEF1A may be differently regulated at post-transcriptional level in breast cancer progression

Eukaryotic translation elongation factor 1A exists as two 98 % homologous isoforms: eEF1A1 (A1) and eEF1A2 (A2) which are tissue and development specific. Despite high homology in an open reading frame (ORF) region, mRNAs coding for eEF1A1 and eEF1A2 are different in their untranslated regions (UTR)...

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Bibliographic Details
Main Authors: Vislovukh, A.A., Naumovets, M.G., Kovalenko, M.I., Groisman, R.S., Groisman, I.S., Negrutskii, B.S., El'skaya, A.V.
Format: Article
Language:English
Published: Інститут молекулярної біології і генетики НАН України 2013
Series:Вiopolymers and Cell
Subjects:
Genomics, Transcriptomics and Proteomics
Online Access:http://dspace.nbuv.gov.ua/handle/123456789/152495
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http://dspace.nbuv.gov.ua/handle/123456789/152495

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