Semi-quantitative model of the gating of KcsA ion channel. 2. Dynamic self-organization model of the gating
The aim of this series of papers is to develop the semi-quantitative theory of the gating of KcsA channel. Methods. For this purpose available structural and electrophysiological data and the results of molecular dynamics simulations were used in the context of the concept of dynamical self-organiza...
Збережено в:
| Дата: | 2009 |
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| Автори: | , , , , |
| Формат: | Стаття |
| Мова: | English |
| Опубліковано: |
Інститут молекулярної біології і генетики НАН України
2009
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| Назва видання: | Вiopolymers and Cell |
| Теми: | |
| Онлайн доступ: | http://dspace.nbuv.gov.ua/handle/123456789/153307 |
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| Назва журналу: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Цитувати: | Semi-quantitative model of the gating of KcsA ion channel. 2. Dynamic self-organization model of the gating / V.N. Kharkyanen, S.O. Yesylevskyy, N.M. Berezetskaya, C. Boiteux, Ch. Ramseyer // Biopolymers and Cell. — 2009. — Т. 25, № 6. — С. 476-483. — Бібліогр.: 16 назв. — англ. |
Репозитарії
Digital Library of Periodicals of National Academy of Sciences of Ukraine| Резюме: | The aim of this series of papers is to develop the semi-quantitative theory of the gating of KcsA channel. Methods. For this purpose available structural and electrophysiological data and the results of molecular dynamics simulations were used in the context of the concept of dynamical self-organization. In the second paper we describe the principles of dynamic self-organization and develop the theory of KcsA channel gating based on this concept. Conclusions. Present work is the first successful attempt of combining the structure and dynamics of real protein and the general concept of dynamic self-organization. |
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