Energetics of ion competition in the DEKA selectivity filter of neuronal sodium channels

• Дата: 2015
• Автори: Boda, D., Leaf, G., Fonseca, J., Eisenberg, B.
• Формат: Стаття
• Мова: English
• Опубліковано: Інститут фізики конденсованих систем НАН України 2015
• Назва видання: Condensed Matter Physics
• Онлайн доступ: http://dspace.nbuv.gov.ua/handle/123456789/153512
• Назва журналу: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Цитувати: Energetics of ion competition in the DEKA selectivity filter of neuronal sodium channels / D. Boda, G. Leaf, J. Fonseca, B. Eisenberg // Condensed Matter Physics. — 2015. — Т. 18, № 1. — С. 13601:1-14. — Бібліогр.: 75 назв. — англ.

The energetics of ionic selectivity in the neuronal sodium channels is studied. A simple model constructed for the selectivity filter of the channel is used. The selectivity filter of this channel type contains aspartate (D), glutamate (E), lysine (K), and alanine (A) residues (the DEKA locus). We u...