Genetic and epigenetic changes in malignant cells of tumors of urogenital organs
More than 90 % of human malignant neoplasms are presented by epithelial tumors. Cancer of urogenital organs is a serious problem because of wide spread of disease and high mortality rates. Tumorogenesis is associated with different defects of genetic apparatus of cells as well as epigenetic factors...
Збережено в:
| Дата: | 2010 |
|---|---|
| Автор: | |
| Формат: | Стаття |
| Мова: | English |
| Опубліковано: |
Інститут молекулярної біології і генетики НАН України
2010
|
| Назва видання: | Вiopolymers and Cell |
| Теми: | |
| Онлайн доступ: | http://dspace.nbuv.gov.ua/handle/123456789/154217 |
| Теги: |
Додати тег
Немає тегів, Будьте першим, хто поставить тег для цього запису!
|
| Назва журналу: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Цитувати: | Genetic and epigenetic changes in malignant cells of tumors of urogenital organs / V.V. Gordiyuk // Вiopolymers and Cell. — 2010. — Т. 26, № 6. — С. 450-460. — Бібліогр.: 100 назв. — англ, рос. |
Репозитарії
Digital Library of Periodicals of National Academy of Sciences of Ukraine| Резюме: | More than 90 % of human malignant neoplasms are presented by epithelial tumors. Cancer of urogenital organs is a serious problem because of wide spread of disease and high mortality rates. Tumorogenesis is associated with different defects of genetic apparatus of cells as well as epigenetic factors (DNA methylation disorders, chromatin reorganizations in processes of histones modifications, regulation of gene expression with small non-coding RNAs). In this review we analyzed genetic and epigenetic changes in the urogenital tumors. |
|---|