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Increased antitumor efficiency and reduced negative side effects in laboratory mice of 4-thiazolidinone derivatives in complexes with PEG-containing polymeric nanocarrier

Aim. To study an anticancer activity and to measure cytological and enzymatic indicators of general toxicity of 4-thiazolidinone-based compounds (Les-3288, Les-3833) in the NK/Ly lymphoma grafted to BALB/C mice. Methods. BALB/C mice were implanted with the ascitic NK/Ly lymphoma and treated for 14 d...

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Bibliographic Details
Main Authors:	Kobylinska, L.I., Skorohyd, N.R., Klyuchivska, O.Yu., Mitina, N.E., Zaichenko, A.S., Lesyk, R.B., Zimenkovsky, B.S., Stoika, R.S.
Format:	Article
Language:	English
Published:	2018
Series:	Інститут молекулярної біології і генетики НАН України
Subjects:	Bioorganic Chemistry
Online Access:	http://dspace.nbuv.gov.ua/handle/123456789/154393
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Increased antitumor efficiency and reduced negative side effects in laboratory mice of 4-thiazolidinone derivatives in complexes with PEG-containing polymeric nanocarrier

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