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Some new data concerning the mutagenic action of DNA
It is shown that spermatozoa of Drosophila melanogaster can transfer molecules of exogenous DNA (or their fragments) from a solution of this DNA injected into the haemocel of an adult male into the ooplasm of the egg. As a result, mutations induced in the descendants arise both in the paternal and t...
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Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Інститут молекулярної біології і генетики НАН України
1994
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Series: | Биополимеры и клетка |
Online Access: | http://dspace.nbuv.gov.ua/handle/123456789/154712 |
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Summary: | It is shown that spermatozoa of Drosophila melanogaster can transfer molecules of exogenous DNA (or their fragments) from a solution of this DNA injected into the haemocel of an adult male into the ooplasm of the egg. As a result, mutations induced in the descendants arise both in the paternal and the maternal chromosomes obtained by them. The mutagenic effect of exogenous DNA has a prolonged character inducing mutations in the descendants during many cell generations after DNA-treatment of their father. The mechanism of such a prolongation of the mutagenic action of DNA is discussed. |
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