The potential mRNA target sites for the ribosomal protein L10 found in Streptomyces griseus and S. coelicolor give evidence for the autogenous regulation of expression of the rplJL genes

The potential mRNA target sites for the ribosomal protein L10 found in Streptomyces griseus and S. coelicolor give evidence for the autogenous regulation of expression of the rplJL genes

On the basis of structural similarity between the m- and rRNA binding sites which underlies the molecular mechanism of the autogenous control of expression of the rplJL genes, mediated in prokaryotic organisms by ribosomal protein L10, we attempted to find the potential mRNA target sites in S. grise...

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Видавець:Інститут молекулярної біології і генетики НАН України
Дата:1995
Автор: Paton, E.B.
Формат: Стаття
Мова:English
Опубліковано: Інститут молекулярної біології і генетики НАН України 1995
Назва видання:Биополимеры и клетка
Онлайн доступ:http://dspace.nbuv.gov.ua/handle/123456789/155628
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Цитувати:The potential mRNA target sites for the ribosomal protein L10 found in Streptomyces griseus and S. coelicolor give evidence for the autogenous regulation of expression of the rplJL genes / E.В. Paton // Биополимеры и клетка. — 1995. — Т. 11, № 1. — С. 40-44. — Бібліогр.: 17 назв. — англ.

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Digital Library of Periodicals of National Academy of Sciences of Ukraine
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spelling irk-123456789-1556282019-06-18T01:26:23Z The potential mRNA target sites for the ribosomal protein L10 found in Streptomyces griseus and S. coelicolor give evidence for the autogenous regulation of expression of the rplJL genes Paton, E.B. On the basis of structural similarity between the m- and rRNA binding sites which underlies the molecular mechanism of the autogenous control of expression of the rplJL genes, mediated in prokaryotic organisms by ribosomal protein L10, we attempted to find the potential mRNA target sites in S. griseus and S. coelicolor. The potential targets found in both species of Streptomyces are of highly conserved structure and contain elements similar with the L10 binding domain of the 23S RNA. Compared to the L10, mRNA targets of Enterobacteria, Thermotoga maritima and Synechocystis, the target sites of Streptomyces contain a larger number of conserved and specific structural elements, similar in both analyzed species. Comparison of the structural organization of the "Streptomyces" and "Enterobacterial" types of the L10 mRNA targets with the structure of the L10 binding domain in the 23S RNA reveals that the elements, conserved in all the mentioned targets, are located in the ssA and dsA regions. The structure of the potential L10 mRNA target sites, which mimic the rRNA target of the regulatory ribosomal protein L10, gives evidence for the autogenous L1-0mediated control of expression of the rplJL genes in Streptomyces. Описано структурові особливості виявленого у представників Streptomyces постійно­го сайта зв'язування рибосомного білка L10, який розміщується в лідерній послідов­ності, що передує генам rplJL. Консервативність структурової організації сайта у двох видів Streptomyces і значна подібність структури до 23S мРНК свідчать про аутогенну регуляцію генів rplJL стрептоміцетів рибосомним білком L10. Описаны структурные особенности обнаруженного у представителей Streptomyces (Streptomyces griseus и Streptomyces coelicolor) потенциального сайта связывания рибосомного белка L10. расположенного в лидерной последовательности, предшествующей генам rplJL. Консервативность структурной организации сайта у двух видов Streptonmyces и высокое подобие структуры с 23S мРНК свидетельствуют об аутогенной регуляции экспрессии генов rplJL стриптомицетов рибосомным белком L10. 1995 Article The potential mRNA target sites for the ribosomal protein L10 found in Streptomyces griseus and S. coelicolor give evidence for the autogenous regulation of expression of the rplJL genes / E.В. Paton // Биополимеры и клетка. — 1995. — Т. 11, № 1. — С. 40-44. — Бібліогр.: 17 назв. — англ. 0233-7657 DOI: http://dx.doi.org/10.7124/bc.0003D0 http://dspace.nbuv.gov.ua/handle/123456789/155628 577.21 en Биополимеры и клетка Інститут молекулярної біології і генетики НАН України
institution Digital Library of Periodicals of National Academy of Sciences of Ukraine
collection DSpace DC
language English
description On the basis of structural similarity between the m- and rRNA binding sites which underlies the molecular mechanism of the autogenous control of expression of the rplJL genes, mediated in prokaryotic organisms by ribosomal protein L10, we attempted to find the potential mRNA target sites in S. griseus and S. coelicolor. The potential targets found in both species of Streptomyces are of highly conserved structure and contain elements similar with the L10 binding domain of the 23S RNA. Compared to the L10, mRNA targets of Enterobacteria, Thermotoga maritima and Synechocystis, the target sites of Streptomyces contain a larger number of conserved and specific structural elements, similar in both analyzed species. Comparison of the structural organization of the "Streptomyces" and "Enterobacterial" types of the L10 mRNA targets with the structure of the L10 binding domain in the 23S RNA reveals that the elements, conserved in all the mentioned targets, are located in the ssA and dsA regions. The structure of the potential L10 mRNA target sites, which mimic the rRNA target of the regulatory ribosomal protein L10, gives evidence for the autogenous L1-0mediated control of expression of the rplJL genes in Streptomyces.
format Article
author Paton, E.B.
spellingShingle Paton, E.B.
The potential mRNA target sites for the ribosomal protein L10 found in Streptomyces griseus and S. coelicolor give evidence for the autogenous regulation of expression of the rplJL genes
Биополимеры и клетка
author_facet Paton, E.B.
author_sort Paton, E.B.
title The potential mRNA target sites for the ribosomal protein L10 found in Streptomyces griseus and S. coelicolor give evidence for the autogenous regulation of expression of the rplJL genes
title_short The potential mRNA target sites for the ribosomal protein L10 found in Streptomyces griseus and S. coelicolor give evidence for the autogenous regulation of expression of the rplJL genes
title_full The potential mRNA target sites for the ribosomal protein L10 found in Streptomyces griseus and S. coelicolor give evidence for the autogenous regulation of expression of the rplJL genes
title_fullStr The potential mRNA target sites for the ribosomal protein L10 found in Streptomyces griseus and S. coelicolor give evidence for the autogenous regulation of expression of the rplJL genes
title_full_unstemmed The potential mRNA target sites for the ribosomal protein L10 found in Streptomyces griseus and S. coelicolor give evidence for the autogenous regulation of expression of the rplJL genes
title_sort potential mrna target sites for the ribosomal protein l10 found in streptomyces griseus and s. coelicolor give evidence for the autogenous regulation of expression of the rpljl genes
publisher Інститут молекулярної біології і генетики НАН України
publishDate 1995
url http://dspace.nbuv.gov.ua/handle/123456789/155628
citation_txt The potential mRNA target sites for the ribosomal protein L10 found in Streptomyces griseus and S. coelicolor give evidence for the autogenous regulation of expression of the rplJL genes / E.В. Paton // Биополимеры и клетка. — 1995. — Т. 11, № 1. — С. 40-44. — Бібліогр.: 17 назв. — англ.
series Биополимеры и клетка
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AT patoneb potentialmrnatargetsitesfortheribosomalproteinl10foundinstreptomycesgriseusandscoelicolorgiveevidencefortheautogenousregulationofexpressionoftherpljlgenes
first_indexed 2023-05-20T17:47:31Z
last_indexed 2023-05-20T17:47:31Z
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