Comparative effects of stearic acid, calcium and magnesium stearates as dopants in model lipid membranes
Comparative studies are reported for calcium and magnesium stearates as well as for stearic acid introduced as dopants in model lipid membranes, both individually and in pairs with cycloserine. Membranotropic effects of the dopants were detected on the basis of complex analysis of phase transition p...
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| Дата: | 2018 |
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| Автори: | , , |
| Формат: | Стаття |
| Мова: | English |
| Опубліковано: |
НТК «Інститут монокристалів» НАН України
2018
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| Назва видання: | Functional Materials |
| Теми: | |
| Онлайн доступ: | http://dspace.nbuv.gov.ua/handle/123456789/157139 |
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| Назва журналу: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Цитувати: | Comparative effects of stearic acid, calcium and magnesium stearates as dopants in model lipid membranes / O.V. Vashchenko, N.A. Kasian, L.V. Budianska // Functional Materials. — 2018. — Т. 25, № 2. — С. 300-307. — Бібліогр.: 41 назв. — англ. |
Репозитарії
Digital Library of Periodicals of National Academy of Sciences of Ukraine| id |
irk-123456789-157139 |
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irk-123456789-1571392019-06-20T01:27:39Z Comparative effects of stearic acid, calcium and magnesium stearates as dopants in model lipid membranes Vashchenko, O.V. Kasian, N.A. Budianska, L.V. Characterization and properties Comparative studies are reported for calcium and magnesium stearates as well as for stearic acid introduced as dopants in model lipid membranes, both individually and in pairs with cycloserine. Membranotropic effects of the dopants were detected on the basis of complex analysis of phase transition parameters obtained by means of differential scanning calorimetry. The individual membranotropic effects increase in order: CaSt < MgSt < StA. It was established that cycloserine extends the temperature range of the membrane ripple phase, unlike the other substances studied. Joint addition of each stearate with cycloserine resulted in a previously unknown synergic membranotropic effect reflected as additional elevation of phase transition temperatures with a non-additive concentration dependence. The synergic effect grows with dopants concentration and appears more pronounced for pre-transition than for main transition. Meanwhile, no synergic effect was observed for stearic acid with cycloserine, and the joint effects could be ranged as: CaSt≥ StA ~ 0. 2018 Article Comparative effects of stearic acid, calcium and magnesium stearates as dopants in model lipid membranes / O.V. Vashchenko, N.A. Kasian, L.V. Budianska // Functional Materials. — 2018. — Т. 25, № 2. — С. 300-307. — Бібліогр.: 41 назв. — англ. 1027-5495 DOI:https://doi.org/10.15407/fm25.02.300 http://dspace.nbuv.gov.ua/handle/123456789/157139 en Functional Materials НТК «Інститут монокристалів» НАН України |
| institution |
Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| collection |
DSpace DC |
| language |
English |
| topic |
Characterization and properties Characterization and properties |
| spellingShingle |
Characterization and properties Characterization and properties Vashchenko, O.V. Kasian, N.A. Budianska, L.V. Comparative effects of stearic acid, calcium and magnesium stearates as dopants in model lipid membranes Functional Materials |
| description |
Comparative studies are reported for calcium and magnesium stearates as well as for stearic acid introduced as dopants in model lipid membranes, both individually and in pairs with cycloserine. Membranotropic effects of the dopants were detected on the basis of complex analysis of phase transition parameters obtained by means of differential scanning calorimetry. The individual membranotropic effects increase in order: CaSt < MgSt < StA. It was established that cycloserine extends the temperature range of the membrane ripple phase, unlike the other substances studied. Joint addition of each stearate with cycloserine resulted in a previously unknown synergic membranotropic effect reflected as additional elevation of phase transition temperatures with a non-additive concentration dependence. The synergic effect grows with dopants concentration and appears more pronounced for pre-transition than for main transition. Meanwhile, no synergic effect was observed for stearic acid with cycloserine, and the joint effects could be ranged as: CaSt≥ StA ~ 0. |
| format |
Article |
| author |
Vashchenko, O.V. Kasian, N.A. Budianska, L.V. |
| author_facet |
Vashchenko, O.V. Kasian, N.A. Budianska, L.V. |
| author_sort |
Vashchenko, O.V. |
| title |
Comparative effects of stearic acid, calcium and magnesium stearates as dopants in model lipid membranes |
| title_short |
Comparative effects of stearic acid, calcium and magnesium stearates as dopants in model lipid membranes |
| title_full |
Comparative effects of stearic acid, calcium and magnesium stearates as dopants in model lipid membranes |
| title_fullStr |
Comparative effects of stearic acid, calcium and magnesium stearates as dopants in model lipid membranes |
| title_full_unstemmed |
Comparative effects of stearic acid, calcium and magnesium stearates as dopants in model lipid membranes |
| title_sort |
comparative effects of stearic acid, calcium and magnesium stearates as dopants in model lipid membranes |
| publisher |
НТК «Інститут монокристалів» НАН України |
| publishDate |
2018 |
| topic_facet |
Characterization and properties |
| url |
http://dspace.nbuv.gov.ua/handle/123456789/157139 |
| citation_txt |
Comparative effects of stearic acid, calcium and magnesium stearates as dopants in model lipid membranes / O.V. Vashchenko, N.A. Kasian, L.V. Budianska // Functional Materials. — 2018. — Т. 25, № 2. — С. 300-307. — Бібліогр.: 41 назв. — англ. |
| series |
Functional Materials |
| work_keys_str_mv |
AT vashchenkoov comparativeeffectsofstearicacidcalciumandmagnesiumstearatesasdopantsinmodellipidmembranes AT kasianna comparativeeffectsofstearicacidcalciumandmagnesiumstearatesasdopantsinmodellipidmembranes AT budianskalv comparativeeffectsofstearicacidcalciumandmagnesiumstearatesasdopantsinmodellipidmembranes |
| first_indexed |
2023-05-20T17:51:01Z |
| last_indexed |
2023-05-20T17:51:01Z |
| _version_ |
1796154236867706880 |