Effects of different concentrations of sodium ions on the self-assembly of amphotericin B and DPPC at the air-water interface
Amphotericin B is a widely used polyene antifungal drug for the treatment of deep fungal infections. This drug could cause pores on the cell membrane. In this work, we used the dipalmitoylphosphatidylcholine monolayer as the model of cell membrane in half. The influence of Na⁺ions on the interaction...
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| Дата: | 2018 |
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| Автори: | , , , |
| Формат: | Стаття |
| Мова: | English |
| Опубліковано: |
НТК «Інститут монокристалів» НАН України
2018
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| Назва видання: | Functional Materials |
| Теми: | |
| Онлайн доступ: | http://dspace.nbuv.gov.ua/handle/123456789/157159 |
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| Назва журналу: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Цитувати: | Effects of different concentrations of sodium ions on the self-assembly of amphotericin B and DPPC at the air-water interface / Juan Wang, Tuo Li, Yahong Ma, Zongcheng Miao // Functional Materials. — 2018. — Т. 25, № 3. — С. 432-438. — Бібліогр.: 15 назв. — англ. |
Репозитарії
Digital Library of Periodicals of National Academy of Sciences of Ukraine| id |
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irk-123456789-1571592019-06-20T01:28:24Z Effects of different concentrations of sodium ions on the self-assembly of amphotericin B and DPPC at the air-water interface Juan Wang Tuo Li Yahong Ma Zongcheng Miao Characterization and properties Amphotericin B is a widely used polyene antifungal drug for the treatment of deep fungal infections. This drug could cause pores on the cell membrane. In this work, we used the dipalmitoylphosphatidylcholine monolayer as the model of cell membrane in half. The influence of Na⁺ions on the interaction between amphotericin B and biomembrane were studied by analysis of phase transition and thermodynamic properties of monolayers. The Na⁺ions may affect the molecular orientation of amphotericin B, and it depends on the concentration of sodium ions. Low concentration of Na⁺ ions has an opposite effect to high concentration of that. The results are helpful for obtaining some information on the influence mechanism in the level of sodium ions on the interaction between amphotericin B and biomembrane in the angle of physics. 2018 Article Effects of different concentrations of sodium ions on the self-assembly of amphotericin B and DPPC at the air-water interface / Juan Wang, Tuo Li, Yahong Ma, Zongcheng Miao // Functional Materials. — 2018. — Т. 25, № 3. — С. 432-438. — Бібліогр.: 15 назв. — англ. 1027-5495 DOI:https://doi.org/10.15407/fm25.03.432 http://dspace.nbuv.gov.ua/handle/123456789/157159 en Functional Materials НТК «Інститут монокристалів» НАН України |
| institution |
Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| collection |
DSpace DC |
| language |
English |
| topic |
Characterization and properties Characterization and properties |
| spellingShingle |
Characterization and properties Characterization and properties Juan Wang Tuo Li Yahong Ma Zongcheng Miao Effects of different concentrations of sodium ions on the self-assembly of amphotericin B and DPPC at the air-water interface Functional Materials |
| description |
Amphotericin B is a widely used polyene antifungal drug for the treatment of deep fungal infections. This drug could cause pores on the cell membrane. In this work, we used the dipalmitoylphosphatidylcholine monolayer as the model of cell membrane in half. The influence of Na⁺ions on the interaction between amphotericin B and biomembrane were studied by analysis of phase transition and thermodynamic properties of monolayers. The Na⁺ions may affect the molecular orientation of amphotericin B, and it depends on the concentration of sodium ions. Low concentration of Na⁺ ions has an opposite effect to high concentration of that. The results are helpful for obtaining some information on the influence mechanism in the level of sodium ions on the interaction between amphotericin B and biomembrane in the angle of physics. |
| format |
Article |
| author |
Juan Wang Tuo Li Yahong Ma Zongcheng Miao |
| author_facet |
Juan Wang Tuo Li Yahong Ma Zongcheng Miao |
| author_sort |
Juan Wang |
| title |
Effects of different concentrations of sodium ions on the self-assembly of amphotericin B and DPPC at the air-water interface |
| title_short |
Effects of different concentrations of sodium ions on the self-assembly of amphotericin B and DPPC at the air-water interface |
| title_full |
Effects of different concentrations of sodium ions on the self-assembly of amphotericin B and DPPC at the air-water interface |
| title_fullStr |
Effects of different concentrations of sodium ions on the self-assembly of amphotericin B and DPPC at the air-water interface |
| title_full_unstemmed |
Effects of different concentrations of sodium ions on the self-assembly of amphotericin B and DPPC at the air-water interface |
| title_sort |
effects of different concentrations of sodium ions on the self-assembly of amphotericin b and dppc at the air-water interface |
| publisher |
НТК «Інститут монокристалів» НАН України |
| publishDate |
2018 |
| topic_facet |
Characterization and properties |
| url |
http://dspace.nbuv.gov.ua/handle/123456789/157159 |
| citation_txt |
Effects of different concentrations of sodium ions on the self-assembly of amphotericin B and DPPC at the air-water interface / Juan Wang, Tuo Li, Yahong Ma, Zongcheng Miao // Functional Materials. — 2018. — Т. 25, № 3. — С. 432-438. — Бібліогр.: 15 назв. — англ. |
| series |
Functional Materials |
| work_keys_str_mv |
AT juanwang effectsofdifferentconcentrationsofsodiumionsontheselfassemblyofamphotericinbanddppcattheairwaterinterface AT tuoli effectsofdifferentconcentrationsofsodiumionsontheselfassemblyofamphotericinbanddppcattheairwaterinterface AT yahongma effectsofdifferentconcentrationsofsodiumionsontheselfassemblyofamphotericinbanddppcattheairwaterinterface AT zongchengmiao effectsofdifferentconcentrationsofsodiumionsontheselfassemblyofamphotericinbanddppcattheairwaterinterface |
| first_indexed |
2023-05-20T17:51:21Z |
| last_indexed |
2023-05-20T17:51:21Z |
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1796154249000779776 |