Characterization of lipids A of Ralstonia solanacearum lipopolysaccharides

• Дата: 2004
• Автори: Varbanets, L.D., Brovarskaya, O.S., Vasiliev, V.N., Vinarskaya, N.V., Gogoman, I.V.
• Формат: Стаття
• Мова: English
• Опубліковано: Інститут молекулярної біології і генетики НАН України 2004
• Назва видання: Біополімери і клітина
• Теми: Структура та функції біополімерів
• Онлайн доступ: http://dspace.nbuv.gov.ua/handle/123456789/157975
• Назва журналу: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Цитувати: Characterization of lipids A of Ralstonia solanacearum lipopolysaccharides / L.D. Varbanets, O.S. Brovarskaya, V.N. Vasiliev, N.V. Vinarskaya, I.V. Gogoman // Біополімери і клітина. — 2004. — Т. 20, № 5. — С. 398-401. — Бібліогр.: 9 назв. — англ.

The analysis of fatty acid profiles of lipopolysacharides has shown that R. solanacearum strains tested may be divided into two groups. The first group is represented by R. solanacearum strains (5712, 7945, 7955 and 8110) the lipids A of which contained hydroxylated fatty acids with long chains: 3-hydroxytetradecanoic, 2-hydroxyhexadecanoic and 2-hydroxyoctadecanoic. The second group was represented by R. solanacearum strains the lipids A of which contained hydroxylated fatty acids with short chains: 3-hydroxydecanoic, 2-hydroxydodecanoic and 3-hydroxydodecanoic. 3-hydroxytetradecanoic acid was observed in a small amount. A comparative analysis of the fatty acid composition and biological activity gives a possibility to suppose that 3-hydroxytetradecanoic, 2-hydroxyhexadecanoic and 2-hydroxyoctadecanoic acids may be responsible for the toxicity and pyrogenicity of the lipopolysaccharides tested.