Современные подходы к лечению анемии у больных со злокачественными новообразованиями

The importance of hemoglobin levels in determining the quality of life of cancer patients receiving chemotherapy has become increasingly clear both from randomized studies. It was first approved for the treatment of anemia in patients with chronic renal disease. Before recombinant human erythropoiet...

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Збережено в:
Бібліографічні деталі
Дата:2008
Автор: Бессмельцев, С.С.
Формат: Стаття
Мова:Russian
Опубліковано: Iнститут експериментальної патології, онкології і радіобіології ім. Р. Є. Кавецького 2008
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Онлайн доступ:http://dspace.nbuv.gov.ua/handle/123456789/2344
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Назва журналу:Digital Library of Periodicals of National Academy of Sciences of Ukraine
Цитувати:Современные подходы к лечению анемии у больных со злокачественными новообразованиями / С.С. Бессмельцев // Онкологія. — 2008. — Т. 10, N 2. — С. 275-283. — Бібліогр.: 65 назв. — рос.

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Digital Library of Periodicals of National Academy of Sciences of Ukraine
Опис
Резюме:The importance of hemoglobin levels in determining the quality of life of cancer patients receiving chemotherapy has become increasingly clear both from randomized studies. It was first approved for the treatment of anemia in patients with chronic renal disease. Before recombinant human erythropoietin (rEPO) erythropoietin was available, blood transfusion was the only treatment option for severe cancer-related anemia. Potential complications associated with blood transfusion are transmission of infectious diseases, transfusion reactions, alloimmunization, over-transfusion and immune modulation with possible adverse effects on tumor growth. It is performed the analyses of effectiveness of rEPO therapy in any hematological malignancies and cancer patients and shown predictors efficiency of this therapy. To update the American Society of Hematology/American Society of Clinical Oncology (ASH/ASCO, 2007) recommendations for the use of rEPO.