The impact of colostrum on brain development of the newborn pigs

• Дата: 2012
• Автори: Goncharova, K.O., Osadchenko, I.O., Kovalenko, T.M., Ushakova, G.O., Pierzynowski, S.G., Skibo, G.G.
• Формат: Стаття
• Мова: English
• Опубліковано: Кримський науковий центр НАН України і МОН України 2012
• Назва видання: Таврический медико-биологический вестник
• Теми: Оригинальные статьи
• Онлайн доступ: http://dspace.nbuv.gov.ua/handle/123456789/44447
• Назва журналу: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Цитувати: The impact of colostrum on brain development of the newborn pigs / K.O. Goncharova, I.O. Osadchenko, T.M. Kovalenko, G.O. Ushakova, S.G. Pierzynowski, G.G. Skibo // Таврический медико-биологический вестник. — 2012. — Т. 15, № 3, ч. 1 (59). — С. 69-72. — Бібліогр.: 5 назв. — англ.

Colostrum is a source of many bioactive components including antibodies (IgG) as suggested protecting the newborns against infection. In this study we aimed to evaluate the role of colostrum for the brain development in newborn pigs. The hippocampal neurons and microglial cells were identified by specific antibodies and analyzed with confocal microscope and the morphometric assay was provided. The piglets deprived of colostrum revealed a reduction in postnatal hippocampal neuro and microgliogenesis. Feeding with elementary diet instead of colostrum didn’t help physiological postnatal brain development. Addition of IgG to elementary diet improved the neurogenesis and supported immune status of the brain supporting the importance of natural feeding in the first weeks of life.