Формализованный анализ адаптивного реагирования клетки на дефицит энергии
To find causal relations between the cellular energy, alterations of mitochondria, and the cellular mechanism of reactive adaptation (MRA) under exogenous stimuli, a formal analysis is performed. It is shown that there are four main consumers (biosynthesis, homeostasis, reparative and compensatory s...
Збережено в:
| Дата: | 2008 |
|---|---|
| Автори: | , |
| Формат: | Стаття |
| Мова: | Russian |
| Опубліковано: |
Видавничий дім "Академперіодика" НАН України
2008
|
| Теми: | |
| Онлайн доступ: | http://dspace.nbuv.gov.ua/handle/123456789/6240 |
| Теги: |
Додати тег
Немає тегів, Будьте першим, хто поставить тег для цього запису!
|
| Назва журналу: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Цитувати: | Формализованный анализ адаптивного реагирования клетки на дефицит энергии / Р.Д. Григорян, Е. Г. Лябах // Доп. НАН України. — 2008. — № 11. — С. 145-151. — Бібліогр.: 15 назв. — рос. |
Репозитарії
Digital Library of Periodicals of National Academy of Sciences of Ukraine| Резюме: | To find causal relations between the cellular energy, alterations of mitochondria, and the cellular mechanism of reactive adaptation (MRA) under exogenous stimuli, a formal analysis is performed. It is shown that there are four main consumers (biosynthesis, homeostasis, reparative and compensatory syntheses) of cell energy. Violating the cellular homeostasis, the exogenous factors decrease the part of energy necessary to provide the biosynthesis. Intermediate chemical agents of the strangulated biosynthesis activate a cascade of transformations leading to an enlargement of both the mitochondrial power and the energy production intensity. This negative feed-back contour is the essence of MRA that maintains the process of decentralized adaptation of a multicellular organism to environmental shifts. |
|---|