Formation of multicellular aggregates under different conditions of microenvironment
Multicellular aggregates (spheroids) represent an intermittent level between monolayer growing cells and tissue culture. Spheroids are rather objective model of the three-dimensional growth and organization, the cell-to-cell interactions and influence of microenvironmental conditions on tumour micro...
Збережено в:
Дата: | 2010 |
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Автори: | , , , |
Формат: | Стаття |
Мова: | English |
Опубліковано: |
Інститут клітинної біології та генетичної інженерії НАН України
2010
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Назва видання: | Цитология и генетика |
Теми: | |
Онлайн доступ: | http://dspace.nbuv.gov.ua/handle/123456789/66677 |
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Назва журналу: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
Цитувати: | Formation of multicellular aggregates under different conditions of microenvironment / L. Garmanchouk, O. Perepelytsina, M. Sydorenko, L.I. Ostapchenko // Цитология и генетика. — 2010. — Т. 44, № 1. — С. 25-29. — Бібліогр.: 10 назв. — рос. |
Репозитарії
Digital Library of Periodicals of National Academy of Sciences of UkraineРезюме: | Multicellular aggregates (spheroids) represent an intermittent level between monolayer growing cells and tissue culture. Spheroids are rather objective model of the three-dimensional growth and organization, the cell-to-cell interactions and influence of microenvironmental conditions on tumour microaggregates. In our work formation and growth of spheroids depends on concentration of CMC and FCS. Conditions of microenvironment influence on intensiveness of proliferation as well as on cells adhesiveness and formation of microaggregates. |
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