Low-temperature ¹Н NМR spectroscopic study of hydration properties of a hybrid system based on nanosilica, DNA and doxorubicin in the presence of C₆₀ fullerene

The structure of hydrate cover layers of SiO₂–DNA–Dox (where Dox: doxorubicin) and SiO₂–DNA–Dox–C₆₀ fullerene hybrids was studied by means of low-temperature ¹H NMR spectroscopy in tetrachloromethane. The hydration properties of SiO₂–DNA–Dox nanomaterials combined with fullerenes and their derivativ...

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Veröffentlicht in:Физика низких температур
Datum:2014
Hauptverfasser: Turov, V.V., Prylutskyy, Yu.I., Ugnivenko, A.P., Barvinchenko, V.N., Krupskaya, T.V., Tsierkezos, N.G., Ritter, U.
Format: Artikel
Sprache:English
Veröffentlicht: Фізико-технічний інститут низьких температур ім. Б.І. Вєркіна НАН України 2014
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Online Zugang:https://nasplib.isofts.kiev.ua/handle/123456789/119438
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Назва журналу:Digital Library of Periodicals of National Academy of Sciences of Ukraine
Zitieren:Low-temperature ¹Н NМR spectroscopic study of hydration properties of a hybrid system based on nanosilica, DNA and doxorubicin in the presence of C₆₀ fullerene / V.V. Turov, Yu.I. Prylutskyy, A.P. Ugnivenko, V.N. Barvinchenko, T.V. Krupskaya, N.G. Tsierkezos, U. Ritter // Физика низких температур. — 2014. — Т. 40, № 3. — С. 309-316. — Бібліогр.: 26 назв. — англ.

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Digital Library of Periodicals of National Academy of Sciences of Ukraine
id nasplib_isofts_kiev_ua-123456789-119438
record_format dspace
spelling Turov, V.V.
Prylutskyy, Yu.I.
Ugnivenko, A.P.
Barvinchenko, V.N.
Krupskaya, T.V.
Tsierkezos, N.G.
Ritter, U.
2017-06-06T19:49:17Z
2017-06-06T19:49:17Z
2014
Low-temperature ¹Н NМR spectroscopic study of hydration properties of a hybrid system based on nanosilica, DNA and doxorubicin in the presence of C₆₀ fullerene / V.V. Turov, Yu.I. Prylutskyy, A.P. Ugnivenko, V.N. Barvinchenko, T.V. Krupskaya, N.G. Tsierkezos, U. Ritter // Физика низких температур. — 2014. — Т. 40, № 3. — С. 309-316. — Бібліогр.: 26 назв. — англ.
0132-6414
PACS 61.05.Qr, 61.46.–w, 82.56.Ub
https://nasplib.isofts.kiev.ua/handle/123456789/119438
The structure of hydrate cover layers of SiO₂–DNA–Dox (where Dox: doxorubicin) and SiO₂–DNA–Dox–C₆₀ fullerene hybrids was studied by means of low-temperature ¹H NMR spectroscopy in tetrachloromethane. The hydration properties of SiO₂–DNA–Dox nanomaterials combined with fullerenes and their derivatives are extremely important for their further use as therapeutics in cancer treatment and for safety reasons. The findings reveal that the hydration properties of the hybrids differ from those of the solid DNA particulates or SiO₂–DNA systems due to the existence of different types of water clusters, namely the weakly- (WAW) and stronglyassociated water (SAW) clusters. For SAW clusters the radial distributions as well as the distributions of change in Gibbs free energy due to adsorptive interactions at the surfaces of the investigated systems were obtained.
en
Фізико-технічний інститут низьких температур ім. Б.І. Вєркіна НАН України
Физика низких температур
Наноструктуры при низких температурах
Low-temperature ¹Н NМR spectroscopic study of hydration properties of a hybrid system based on nanosilica, DNA and doxorubicin in the presence of C₆₀ fullerene
Article
published earlier
institution Digital Library of Periodicals of National Academy of Sciences of Ukraine
collection DSpace DC
title Low-temperature ¹Н NМR spectroscopic study of hydration properties of a hybrid system based on nanosilica, DNA and doxorubicin in the presence of C₆₀ fullerene
spellingShingle Low-temperature ¹Н NМR spectroscopic study of hydration properties of a hybrid system based on nanosilica, DNA and doxorubicin in the presence of C₆₀ fullerene
Turov, V.V.
Prylutskyy, Yu.I.
Ugnivenko, A.P.
Barvinchenko, V.N.
Krupskaya, T.V.
Tsierkezos, N.G.
Ritter, U.
Наноструктуры при низких температурах
title_short Low-temperature ¹Н NМR spectroscopic study of hydration properties of a hybrid system based on nanosilica, DNA and doxorubicin in the presence of C₆₀ fullerene
title_full Low-temperature ¹Н NМR spectroscopic study of hydration properties of a hybrid system based on nanosilica, DNA and doxorubicin in the presence of C₆₀ fullerene
title_fullStr Low-temperature ¹Н NМR spectroscopic study of hydration properties of a hybrid system based on nanosilica, DNA and doxorubicin in the presence of C₆₀ fullerene
title_full_unstemmed Low-temperature ¹Н NМR spectroscopic study of hydration properties of a hybrid system based on nanosilica, DNA and doxorubicin in the presence of C₆₀ fullerene
title_sort low-temperature ¹н nмr spectroscopic study of hydration properties of a hybrid system based on nanosilica, dna and doxorubicin in the presence of c₆₀ fullerene
author Turov, V.V.
Prylutskyy, Yu.I.
Ugnivenko, A.P.
Barvinchenko, V.N.
Krupskaya, T.V.
Tsierkezos, N.G.
Ritter, U.
author_facet Turov, V.V.
Prylutskyy, Yu.I.
Ugnivenko, A.P.
Barvinchenko, V.N.
Krupskaya, T.V.
Tsierkezos, N.G.
Ritter, U.
topic Наноструктуры при низких температурах
topic_facet Наноструктуры при низких температурах
publishDate 2014
language English
container_title Физика низких температур
publisher Фізико-технічний інститут низьких температур ім. Б.І. Вєркіна НАН України
format Article
description The structure of hydrate cover layers of SiO₂–DNA–Dox (where Dox: doxorubicin) and SiO₂–DNA–Dox–C₆₀ fullerene hybrids was studied by means of low-temperature ¹H NMR spectroscopy in tetrachloromethane. The hydration properties of SiO₂–DNA–Dox nanomaterials combined with fullerenes and their derivatives are extremely important for their further use as therapeutics in cancer treatment and for safety reasons. The findings reveal that the hydration properties of the hybrids differ from those of the solid DNA particulates or SiO₂–DNA systems due to the existence of different types of water clusters, namely the weakly- (WAW) and stronglyassociated water (SAW) clusters. For SAW clusters the radial distributions as well as the distributions of change in Gibbs free energy due to adsorptive interactions at the surfaces of the investigated systems were obtained.
issn 0132-6414
url https://nasplib.isofts.kiev.ua/handle/123456789/119438
citation_txt Low-temperature ¹Н NМR spectroscopic study of hydration properties of a hybrid system based on nanosilica, DNA and doxorubicin in the presence of C₆₀ fullerene / V.V. Turov, Yu.I. Prylutskyy, A.P. Ugnivenko, V.N. Barvinchenko, T.V. Krupskaya, N.G. Tsierkezos, U. Ritter // Физика низких температур. — 2014. — Т. 40, № 3. — С. 309-316. — Бібліогр.: 26 назв. — англ.
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first_indexed 2025-11-30T16:03:12Z
last_indexed 2025-11-30T16:03:12Z
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