Correlations between molecular parameters of guest substances and their effect on model lipid membranes
Effect of guests molecules on phase transitions of model lipid membranes was studied by differential scanning calorimetry. Membranotropic action of guest molecules was estimated from the shift of "gel - liquid crystal" phase transition temperature of lipid membranes. Relationships between...
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| Veröffentlicht in: | Functional Materials |
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| Datum: | 2016 |
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| Sprache: | English |
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НТК «Інститут монокристалів» НАН України
2016
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| Назва журналу: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Zitieren: | Correlations between molecular parameters of guest substances and their effect on model lipid membranes / A.O. Sadchenko, O.V. Vashchenko, N.A. Kasian, L.V. Budianska, L.N. Lisetski // Functional Materials. — 2016. — Т. 23, № 2. — С. 230-235. — Бібліогр.: 31 назв. — англ. |
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Sadchenko, A.O. Vashchenko, O.V. Kasian, N.A. Budianska, L.V. Lisetski, L.N. 2017-06-12T14:12:57Z 2017-06-12T14:12:57Z 2016 Correlations between molecular parameters of guest substances and their effect on model lipid membranes / A.O. Sadchenko, O.V. Vashchenko, N.A. Kasian, L.V. Budianska, L.N. Lisetski // Functional Materials. — 2016. — Т. 23, № 2. — С. 230-235. — Бібліогр.: 31 назв. — англ. 1027-5495 DOI: dx.doi.org/10.15407/fm23.02.230 https://nasplib.isofts.kiev.ua/handle/123456789/120623 Effect of guests molecules on phase transitions of model lipid membranes was studied by differential scanning calorimetry. Membranotropic action of guest molecules was estimated from the shift of "gel - liquid crystal" phase transition temperature of lipid membranes. Relationships between membranotropic action and molecular parameters of guest molecules (volume, surface area, dipole moment, anisometry, lipophilicity coefficient, fraction of the polar area, etc.) were examined. For most of the lipophilic substances studied a high linear correlations between membranotropic action and lipophilicity coefficient (r = 0.86), as well as fraction of polar molecular area (r = -0.83) were established. For hydrophilic substances such correlations were not found. For groups of substances with similar chemical nature (glycerol derivatives, ammonium compounds), high linear correlations (r > 0.8) were established between membranotropic action and such molecular parameters as surface area, volume, dipole moment. en НТК «Інститут монокристалів» НАН України Functional Materials Characterization and properties Correlations between molecular parameters of guest substances and their effect on model lipid membranes Article published earlier |
| institution |
Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| collection |
DSpace DC |
| title |
Correlations between molecular parameters of guest substances and their effect on model lipid membranes |
| spellingShingle |
Correlations between molecular parameters of guest substances and their effect on model lipid membranes Sadchenko, A.O. Vashchenko, O.V. Kasian, N.A. Budianska, L.V. Lisetski, L.N. Characterization and properties |
| title_short |
Correlations between molecular parameters of guest substances and their effect on model lipid membranes |
| title_full |
Correlations between molecular parameters of guest substances and their effect on model lipid membranes |
| title_fullStr |
Correlations between molecular parameters of guest substances and their effect on model lipid membranes |
| title_full_unstemmed |
Correlations between molecular parameters of guest substances and their effect on model lipid membranes |
| title_sort |
correlations between molecular parameters of guest substances and their effect on model lipid membranes |
| author |
Sadchenko, A.O. Vashchenko, O.V. Kasian, N.A. Budianska, L.V. Lisetski, L.N. |
| author_facet |
Sadchenko, A.O. Vashchenko, O.V. Kasian, N.A. Budianska, L.V. Lisetski, L.N. |
| topic |
Characterization and properties |
| topic_facet |
Characterization and properties |
| publishDate |
2016 |
| language |
English |
| container_title |
Functional Materials |
| publisher |
НТК «Інститут монокристалів» НАН України |
| format |
Article |
| description |
Effect of guests molecules on phase transitions of model lipid membranes was studied by differential scanning calorimetry. Membranotropic action of guest molecules was estimated from the shift of "gel - liquid crystal" phase transition temperature of lipid membranes. Relationships between membranotropic action and molecular parameters of guest molecules (volume, surface area, dipole moment, anisometry, lipophilicity coefficient, fraction of the polar area, etc.) were examined. For most of the lipophilic substances studied a high linear correlations between membranotropic action and lipophilicity coefficient (r = 0.86), as well as fraction of polar molecular area (r = -0.83) were established. For hydrophilic substances such correlations were not found. For groups of substances with similar chemical nature (glycerol derivatives, ammonium compounds), high linear correlations (r > 0.8) were established between membranotropic action and such molecular parameters as surface area, volume, dipole moment.
|
| issn |
1027-5495 |
| url |
https://nasplib.isofts.kiev.ua/handle/123456789/120623 |
| citation_txt |
Correlations between molecular parameters of guest substances and their effect on model lipid membranes / A.O. Sadchenko, O.V. Vashchenko, N.A. Kasian, L.V. Budianska, L.N. Lisetski // Functional Materials. — 2016. — Т. 23, № 2. — С. 230-235. — Бібліогр.: 31 назв. — англ. |
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| first_indexed |
2025-12-07T20:37:20Z |
| last_indexed |
2025-12-07T20:37:20Z |
| _version_ |
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