Fluorescent Mueller-matrix polarimetry of biological tissues in differentiation of benign and malignant tumors

The work is aimed at investigation of diagnostic efficiency provided by a new azimuthally stable Mueller-matrix method for analyzing laser fluorescence coordinate distributions characterizing biological tissue histological sections. A new model of generalized optical anisotropy of biological tissues...

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Veröffentlicht in:Semiconductor Physics Quantum Electronics & Optoelectronics
Datum:2015
Hauptverfasser: Ushenko, Yu.O., Lakusta, I.I., Olar, O.I., Novakovska, O.Yu.
Format: Artikel
Sprache:English
Veröffentlicht: Інститут фізики напівпровідників імені В.Є. Лашкарьова НАН України 2015
Online Zugang:https://nasplib.isofts.kiev.ua/handle/123456789/121154
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Назва журналу:Digital Library of Periodicals of National Academy of Sciences of Ukraine
Zitieren:Fluorescent Mueller-matrix polarimetry of biological tissues in differentiation of benign and malignant tumors / Yu.O. Ushenko, I.I. Lakusta, O.I. Olar, O.Yu. Novakovska // Semiconductor Physics Quantum Electronics & Optoelectronics. — 2015. — Т. 18, № 1. — С. 181-187. — Бібліогр.: 31 назв. — англ.

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Digital Library of Periodicals of National Academy of Sciences of Ukraine
id nasplib_isofts_kiev_ua-123456789-121154
record_format dspace
spelling Ushenko, Yu.O.
Lakusta, I.I.
Olar, O.I.
Novakovska, O.Yu.
2017-06-13T15:50:37Z
2017-06-13T15:50:37Z
2015
Fluorescent Mueller-matrix polarimetry of biological tissues in differentiation of benign and malignant tumors / Yu.O. Ushenko, I.I. Lakusta, O.I. Olar, O.Yu. Novakovska // Semiconductor Physics Quantum Electronics & Optoelectronics. — 2015. — Т. 18, № 1. — С. 181-187. — Бібліогр.: 31 назв. — англ.
1560-8034
DOI: 10.15407/spqeo18.02.181
PACS 87.50.wp, 87.57.-s, 87.64.-t, 87.85.Pq
https://nasplib.isofts.kiev.ua/handle/123456789/121154
The work is aimed at investigation of diagnostic efficiency provided by a new azimuthally stable Mueller-matrix method for analyzing laser fluorescence coordinate distributions characterizing biological tissue histological sections. A new model of generalized optical anisotropy of biological tissues containing protein networks has been proposed in order to ascertain the processes of laser autofluorescence. The influence of complex mechanisms of both phase anisotropy (linear birefringence and optical activity) and linear (circular) dichroism was taken into account. The interrelations between the azimuthally stable Mueller-matrix elements characterizing laser autofluorescence and different mechanisms of optical anisotropy have been determined. The statistic analysis of coordinate distributions of these Mueller-matrix rotation invariants has been offered. Thereupon the quantitative criteria (statistic moments of the 1st to 4th orders) of differentiation of histological sections of uterus wall tumor – group 1 (dysplasia) and group 2 (adenocarcinoma) have been estimated.
This work was supported by the grants № 0113U003239 and № 0112U002336 from the Ukrainian Foundation for Basic Researches
en
Інститут фізики напівпровідників імені В.Є. Лашкарьова НАН України
Semiconductor Physics Quantum Electronics & Optoelectronics
Fluorescent Mueller-matrix polarimetry of biological tissues in differentiation of benign and malignant tumors
Article
published earlier
institution Digital Library of Periodicals of National Academy of Sciences of Ukraine
collection DSpace DC
title Fluorescent Mueller-matrix polarimetry of biological tissues in differentiation of benign and malignant tumors
spellingShingle Fluorescent Mueller-matrix polarimetry of biological tissues in differentiation of benign and malignant tumors
Ushenko, Yu.O.
Lakusta, I.I.
Olar, O.I.
Novakovska, O.Yu.
title_short Fluorescent Mueller-matrix polarimetry of biological tissues in differentiation of benign and malignant tumors
title_full Fluorescent Mueller-matrix polarimetry of biological tissues in differentiation of benign and malignant tumors
title_fullStr Fluorescent Mueller-matrix polarimetry of biological tissues in differentiation of benign and malignant tumors
title_full_unstemmed Fluorescent Mueller-matrix polarimetry of biological tissues in differentiation of benign and malignant tumors
title_sort fluorescent mueller-matrix polarimetry of biological tissues in differentiation of benign and malignant tumors
author Ushenko, Yu.O.
Lakusta, I.I.
Olar, O.I.
Novakovska, O.Yu.
author_facet Ushenko, Yu.O.
Lakusta, I.I.
Olar, O.I.
Novakovska, O.Yu.
publishDate 2015
language English
container_title Semiconductor Physics Quantum Electronics & Optoelectronics
publisher Інститут фізики напівпровідників імені В.Є. Лашкарьова НАН України
format Article
description The work is aimed at investigation of diagnostic efficiency provided by a new azimuthally stable Mueller-matrix method for analyzing laser fluorescence coordinate distributions characterizing biological tissue histological sections. A new model of generalized optical anisotropy of biological tissues containing protein networks has been proposed in order to ascertain the processes of laser autofluorescence. The influence of complex mechanisms of both phase anisotropy (linear birefringence and optical activity) and linear (circular) dichroism was taken into account. The interrelations between the azimuthally stable Mueller-matrix elements characterizing laser autofluorescence and different mechanisms of optical anisotropy have been determined. The statistic analysis of coordinate distributions of these Mueller-matrix rotation invariants has been offered. Thereupon the quantitative criteria (statistic moments of the 1st to 4th orders) of differentiation of histological sections of uterus wall tumor – group 1 (dysplasia) and group 2 (adenocarcinoma) have been estimated.
issn 1560-8034
url https://nasplib.isofts.kiev.ua/handle/123456789/121154
citation_txt Fluorescent Mueller-matrix polarimetry of biological tissues in differentiation of benign and malignant tumors / Yu.O. Ushenko, I.I. Lakusta, O.I. Olar, O.Yu. Novakovska // Semiconductor Physics Quantum Electronics & Optoelectronics. — 2015. — Т. 18, № 1. — С. 181-187. — Бібліогр.: 31 назв. — англ.
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