Antineoplastic drug NSC631570 modulates functions of hypoxic macrophages

• Published in: Цитология и генетика
• Date: 2013
• Main Authors: Skivka, L.M., Fedorchuk, O.G., Rudic, M.P., Pozur, V.V., Khranovska, N.M., Grom, M.Yu., Nowicky, J.W.
• Format: Article
• Language: English
• Published: Інститут клітинної біології та генетичної інженерії НАН України 2013
• Subjects: Оригинальные работы
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/126597
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Antineoplastic drug NSC631570 modulates functions of hypoxic macrophages / L.M. Skivka, O.G. Fedorchuk, M.P. Rudic, V.V. Pozur, N.M. Khranovska, M.Yu. Grom, J.W. Nowicky // Цитология и генетика. — 2013. — Т. 47, № 5. — С. 70-82. — Бібліогр.: 52 назв. — англ.

Hypoxia is an important factor in the macrophages microenvironment. Many physiological and pathological processes including solid tumor development are characterized by both low oxygen content and presence of macrophages. Tumor-associated hypoxia causes alternative polarization of macrophages in tum...