β-lapachone induces growth inhibition and apoptosis in bladder cancer cells by modulation of BCL-2 family and activation of caspases

• Date: 2006
• Main Authors: Lee, J.I., Choi, D.Y., Chung, H.S., Seo, H.G., Woo, H.J., Choi, B.T., Choi, Y.H.
• Format: Article
• Language: English
• Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2006
• Series: Experimental Oncology
• Subjects: Original contributions
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/134525
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: β-lapachone induces growth inhibition and apoptosis in bladder cancer cells by modulation of BCL-2 family and activation of caspases / J.I. Lee, D.Y. Choi, H.S. Chung, H.G. Seo, H.J. Woo, B.T. Choi, Y.H. Choi // Experimental Oncology. — 2006. — Т. 28, № 1. — С. 30-35. — Бібліогр.: 22 назв. — англ.

Aim: To study in vitro the molecular mechanism of apoptosis caused by b-lapachone, a quinone obtained from the bark of the lapacho tree (Tabebuia avellanedae). Materials and Methods: The study was carried out on human bladder carcinoma T24 cell line. Determination of cell viability was done using tr...