Photochemoprevention of cutaneous neoplasia through natural products

• Veröffentlicht in: Experimental Oncology
• Datum: 2009
• Hauptverfasser: Filip, A., Clichici, S., Daicoviciu, D., Adriana, M., Postescu, I.D., Perde-Schrepler, M., Olteanu, D.
• Format: Artikel
• Sprache: Englisch
• Veröffentlicht: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2009
• Schlagworte: Reviews
• Online Zugang: https://nasplib.isofts.kiev.ua/handle/123456789/134925
• Назва журналу: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Zitieren: Photochemoprevention of cutaneous neoplasia through natural products / A. Filip, S. Clichici, D. Daicoviciu, M. Adriana, I.D. Postescu, M. Perde-Schrepler, D. Olteanu // Experimental Oncology. — 2009. — Т. 31, № 1. — С. 9-15. — Бібліогр.: 62 назв. — англ.

Non-melanoma skin cancers such as squamous cell carcinoma and basal cell carcinoma are the most common types of human tumors,
 representing 30% of the new cases of malignancies diagnosed each year. Ultraviolet radiation (UV) from the sun is a major cause
 of non-melanoma skin cancer in humans. The prevention and mainly the photochemoprevention with natural products represent
 a simple but very effective strategy in the management of cutaneous neoplasia. Here we review the progress in the research of new
 and existing agents developed to protect the skin exposed to UV. We also discuss the current state of knowledge on their photosuppression
 mechanism in humans as well as in animal models, and efficiency in cancer prevention