Expression of the estrogen and progesterone receptors as prognostic factor in serous ovarian cancers

Aim: To study the expression of estrogen receptors (ER) and progesterone receptors (PR) and proliferation marker Ki-67 in ovarian
 tumors using immunohistochemistry, and evaluate possible prognostic significance ofthese markers. Methods: Immunohistochemical
 evaluation of Ki-67, ER a...

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Published in:Experimental Oncology
Date:2009
Main Authors: Buchynska, L.G., Iurchenko, N.P., Grinkevych, V.M., Nesina, I.P., Chekhun, S.V., Svintsitsky, V.S.
Format: Article
Language:English
Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2009
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Online Access:https://nasplib.isofts.kiev.ua/handle/123456789/134930
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Journal Title:Digital Library of Periodicals of National Academy of Sciences of Ukraine
Cite this:Expression of the estrogen and progesterone receptors as prognostic factor in serous ovarian cancers / L.G. Buchynska, N.P. Iurchenko, V.M. Grinkevych, I.P. Nesina, S.V. Chekhun, V.S. Svintsitsky // Experimental Oncology. — 2009. — Т. 31, № 1. — С. 48-51. — Бібліогр.: 21 назв. — англ.

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Digital Library of Periodicals of National Academy of Sciences of Ukraine
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author Buchynska, L.G.
Iurchenko, N.P.
Grinkevych, V.M.
Nesina, I.P.
Chekhun, S.V.
Svintsitsky, V.S.
author_facet Buchynska, L.G.
Iurchenko, N.P.
Grinkevych, V.M.
Nesina, I.P.
Chekhun, S.V.
Svintsitsky, V.S.
citation_txt Expression of the estrogen and progesterone receptors as prognostic factor in serous ovarian cancers / L.G. Buchynska, N.P. Iurchenko, V.M. Grinkevych, I.P. Nesina, S.V. Chekhun, V.S. Svintsitsky // Experimental Oncology. — 2009. — Т. 31, № 1. — С. 48-51. — Бібліогр.: 21 назв. — англ.
collection DSpace DC
container_title Experimental Oncology
description Aim: To study the expression of estrogen receptors (ER) and progesterone receptors (PR) and proliferation marker Ki-67 in ovarian
 tumors using immunohistochemistry, and evaluate possible prognostic significance ofthese markers. Methods: Immunohistochemical
 evaluation of Ki-67, ER and PR expression was performed on serous ovarian cancer (OC) tissue samples from 81 OC patients.
 Results: Serous OC is characterised by high proliferative activity and increased expression of steroid hormone receptors compared
 to nontransfomed ovarian surface epithelium. It has been shown that ER and PR expression levels depend on tumor histologic grade
 and the stage of the disease, and are variable between tumors of the same grade. The ER and PR expression levels correlate with
 OC patients’ survival. Conclusion: Proliferative activity and steroid hormone receptor status along with clinical and morphological
 characteristics of serous OC possess prognostic significance and may be used for evaluation of the disease course
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last_indexed 2025-12-07T19:08:43Z
publishDate 2009
publisher Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
record_format dspace
spelling Buchynska, L.G.
Iurchenko, N.P.
Grinkevych, V.M.
Nesina, I.P.
Chekhun, S.V.
Svintsitsky, V.S.
2018-06-14T11:41:15Z
2018-06-14T11:41:15Z
2009
Expression of the estrogen and progesterone receptors as prognostic factor in serous ovarian cancers / L.G. Buchynska, N.P. Iurchenko, V.M. Grinkevych, I.P. Nesina, S.V. Chekhun, V.S. Svintsitsky // Experimental Oncology. — 2009. — Т. 31, № 1. — С. 48-51. — Бібліогр.: 21 назв. — англ.
1812-9269
https://nasplib.isofts.kiev.ua/handle/123456789/134930
Aim: To study the expression of estrogen receptors (ER) and progesterone receptors (PR) and proliferation marker Ki-67 in ovarian
 tumors using immunohistochemistry, and evaluate possible prognostic significance ofthese markers. Methods: Immunohistochemical
 evaluation of Ki-67, ER and PR expression was performed on serous ovarian cancer (OC) tissue samples from 81 OC patients.
 Results: Serous OC is characterised by high proliferative activity and increased expression of steroid hormone receptors compared
 to nontransfomed ovarian surface epithelium. It has been shown that ER and PR expression levels depend on tumor histologic grade
 and the stage of the disease, and are variable between tumors of the same grade. The ER and PR expression levels correlate with
 OC patients’ survival. Conclusion: Proliferative activity and steroid hormone receptor status along with clinical and morphological
 characteristics of serous OC possess prognostic significance and may be used for evaluation of the disease course
en
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
Experimental Oncology
Original contributions
Expression of the estrogen and progesterone receptors as prognostic factor in serous ovarian cancers
Article
published earlier
spellingShingle Expression of the estrogen and progesterone receptors as prognostic factor in serous ovarian cancers
Buchynska, L.G.
Iurchenko, N.P.
Grinkevych, V.M.
Nesina, I.P.
Chekhun, S.V.
Svintsitsky, V.S.
Original contributions
title Expression of the estrogen and progesterone receptors as prognostic factor in serous ovarian cancers
title_full Expression of the estrogen and progesterone receptors as prognostic factor in serous ovarian cancers
title_fullStr Expression of the estrogen and progesterone receptors as prognostic factor in serous ovarian cancers
title_full_unstemmed Expression of the estrogen and progesterone receptors as prognostic factor in serous ovarian cancers
title_short Expression of the estrogen and progesterone receptors as prognostic factor in serous ovarian cancers
title_sort expression of the estrogen and progesterone receptors as prognostic factor in serous ovarian cancers
topic Original contributions
topic_facet Original contributions
url https://nasplib.isofts.kiev.ua/handle/123456789/134930
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AT nesinaip expressionoftheestrogenandprogesteronereceptorsasprognosticfactorinserousovariancancers
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