Tyrosine kinase inhibitors in treatment of fibrous histiocytoma

Aim: To describe potential beneficial effects of tyrosine kinase inhibitor in the treatment of unresectable/metastatic fibrous histiocytoma. Methods: We report a case of advanced stage fibrous histiocytoma with locally recurrent disease plus lung and bone metastatic deposits. Patient was treated w...

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Veröffentlicht in:Experimental Oncology
Datum:2009
Hauptverfasser: Maur, D., Panou, C., Valachis, A., Kamposioras, K., Tsali, L.
Format: Artikel
Sprache:Englisch
Veröffentlicht: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2009
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Online Zugang:https://nasplib.isofts.kiev.ua/handle/123456789/135111
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Назва журналу:Digital Library of Periodicals of National Academy of Sciences of Ukraine
Zitieren:Tyrosine kinase inhibitors in treatment of fibrous histiocytoma / D. Mauri, C. Panou, A. Valachis, K. Kamposioras, L. Tsali // Experimental Oncology. — 2009. — Т. 31, № 1. — С. 60-61. — Бібліогр.: 18 назв. — англ.

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Digital Library of Periodicals of National Academy of Sciences of Ukraine
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author Maur, D.
Panou, C.
Valachis, A.
Kamposioras, K.
Tsali, L.
author_facet Maur, D.
Panou, C.
Valachis, A.
Kamposioras, K.
Tsali, L.
citation_txt Tyrosine kinase inhibitors in treatment of fibrous histiocytoma / D. Mauri, C. Panou, A. Valachis, K. Kamposioras, L. Tsali // Experimental Oncology. — 2009. — Т. 31, № 1. — С. 60-61. — Бібліогр.: 18 назв. — англ.
collection DSpace DC
container_title Experimental Oncology
description Aim: To describe potential beneficial effects of tyrosine kinase inhibitor in the treatment of unresectable/metastatic fibrous histiocytoma. Methods: We report a case of advanced stage fibrous histiocytoma with locally recurrent disease plus lung and bone metastatic deposits. Patient was treated with the tyrosine kinase inhibitor sunitinib. Results: Treatment with Sunitinib resulted in disease stabilization in the regional lesion and in good partial response for metastatic foci (reduction in number and size). After 13 months of treatment the patient is doing well with no tumor progression. Conclusions: This case appears to be one of the first documentations of beneficial effect and potential long-term benefit of TKIs in the treatment of fibrous histiocytoma.
first_indexed 2025-11-27T23:58:19Z
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language English
last_indexed 2025-11-27T23:58:19Z
publishDate 2009
publisher Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
record_format dspace
spelling Maur, D.
Panou, C.
Valachis, A.
Kamposioras, K.
Tsali, L.
2018-06-14T15:38:44Z
2018-06-14T15:38:44Z
2009
Tyrosine kinase inhibitors in treatment of fibrous histiocytoma / D. Mauri, C. Panou, A. Valachis, K. Kamposioras, L. Tsali // Experimental Oncology. — 2009. — Т. 31, № 1. — С. 60-61. — Бібліогр.: 18 назв. — англ.
1812-9269
https://nasplib.isofts.kiev.ua/handle/123456789/135111
Aim: To describe potential beneficial effects of tyrosine kinase inhibitor in the treatment of unresectable/metastatic fibrous histiocytoma. Methods: We report a case of advanced stage fibrous histiocytoma with locally recurrent disease plus lung and bone metastatic deposits. Patient was treated with the tyrosine kinase inhibitor sunitinib. Results: Treatment with Sunitinib resulted in disease stabilization in the regional lesion and in good partial response for metastatic foci (reduction in number and size). After 13 months of treatment the patient is doing well with no tumor progression. Conclusions: This case appears to be one of the first documentations of beneficial effect and potential long-term benefit of TKIs in the treatment of fibrous histiocytoma.
en
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
Experimental Oncology
Short communications
Tyrosine kinase inhibitors in treatment of fibrous histiocytoma
Article
published earlier
spellingShingle Tyrosine kinase inhibitors in treatment of fibrous histiocytoma
Maur, D.
Panou, C.
Valachis, A.
Kamposioras, K.
Tsali, L.
Short communications
title Tyrosine kinase inhibitors in treatment of fibrous histiocytoma
title_full Tyrosine kinase inhibitors in treatment of fibrous histiocytoma
title_fullStr Tyrosine kinase inhibitors in treatment of fibrous histiocytoma
title_full_unstemmed Tyrosine kinase inhibitors in treatment of fibrous histiocytoma
title_short Tyrosine kinase inhibitors in treatment of fibrous histiocytoma
title_sort tyrosine kinase inhibitors in treatment of fibrous histiocytoma
topic Short communications
topic_facet Short communications
url https://nasplib.isofts.kiev.ua/handle/123456789/135111
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AT panouc tyrosinekinaseinhibitorsintreatmentoffibroushistiocytoma
AT valachisa tyrosinekinaseinhibitorsintreatmentoffibroushistiocytoma
AT kamposiorask tyrosinekinaseinhibitorsintreatmentoffibroushistiocytoma
AT tsalil tyrosinekinaseinhibitorsintreatmentoffibroushistiocytoma