Tyrosine kinase inhibitors in treatment of fibrous histiocytoma
Aim: To describe potential beneficial effects of tyrosine kinase inhibitor in the treatment of unresectable/metastatic fibrous histiocytoma.
 Methods: We report a case of advanced stage fibrous histiocytoma with locally recurrent disease plus lung and bone
 metastatic deposits. Patie...
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| Published in: | Experimental Oncology |
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| Date: | 2009 |
| Main Authors: | , , , , |
| Format: | Article |
| Language: | English |
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Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
2009
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| Online Access: | https://nasplib.isofts.kiev.ua/handle/123456789/135111 |
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| Journal Title: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Cite this: | Tyrosine kinase inhibitors in treatment of fibrous histiocytoma / D. Mauri, C. Panou, A. Valachis, K. Kamposioras, L. Tsali // Experimental Oncology. — 2009. — Т. 31, № 1. — С. 60-61. — Бібліогр.: 18 назв. — англ. |
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Digital Library of Periodicals of National Academy of Sciences of Ukraine| _version_ | 1862599999276187648 |
|---|---|
| author | Maur, D. Panou, C. Valachis, A. Kamposioras, K. Tsali, L. |
| author_facet | Maur, D. Panou, C. Valachis, A. Kamposioras, K. Tsali, L. |
| citation_txt | Tyrosine kinase inhibitors in treatment of fibrous histiocytoma / D. Mauri, C. Panou, A. Valachis, K. Kamposioras, L. Tsali // Experimental Oncology. — 2009. — Т. 31, № 1. — С. 60-61. — Бібліогр.: 18 назв. — англ. |
| collection | DSpace DC |
| container_title | Experimental Oncology |
| description | Aim: To describe potential beneficial effects of tyrosine kinase inhibitor in the treatment of unresectable/metastatic fibrous histiocytoma.
Methods: We report a case of advanced stage fibrous histiocytoma with locally recurrent disease plus lung and bone
metastatic deposits. Patient was treated with the tyrosine kinase inhibitor sunitinib. Results: Treatment with Sunitinib resulted in
disease stabilization in the regional lesion and in good partial response for metastatic foci (reduction in number and size). After
13 months of treatment the patient is doing well with no tumor progression. Conclusions: This case appears to be one of the first
documentations of beneficial effect and potential long-term benefit of TKIs in the treatment of fibrous histiocytoma.
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| first_indexed | 2025-11-27T23:58:19Z |
| format | Article |
| fulltext | |
| id | nasplib_isofts_kiev_ua-123456789-135111 |
| institution | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| issn | 1812-9269 |
| language | English |
| last_indexed | 2025-11-27T23:58:19Z |
| publishDate | 2009 |
| publisher | Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України |
| record_format | dspace |
| spelling | Maur, D. Panou, C. Valachis, A. Kamposioras, K. Tsali, L. 2018-06-14T15:38:44Z 2018-06-14T15:38:44Z 2009 Tyrosine kinase inhibitors in treatment of fibrous histiocytoma / D. Mauri, C. Panou, A. Valachis, K. Kamposioras, L. Tsali // Experimental Oncology. — 2009. — Т. 31, № 1. — С. 60-61. — Бібліогр.: 18 назв. — англ. 1812-9269 https://nasplib.isofts.kiev.ua/handle/123456789/135111 Aim: To describe potential beneficial effects of tyrosine kinase inhibitor in the treatment of unresectable/metastatic fibrous histiocytoma.
 Methods: We report a case of advanced stage fibrous histiocytoma with locally recurrent disease plus lung and bone
 metastatic deposits. Patient was treated with the tyrosine kinase inhibitor sunitinib. Results: Treatment with Sunitinib resulted in
 disease stabilization in the regional lesion and in good partial response for metastatic foci (reduction in number and size). After
 13 months of treatment the patient is doing well with no tumor progression. Conclusions: This case appears to be one of the first
 documentations of beneficial effect and potential long-term benefit of TKIs in the treatment of fibrous histiocytoma. en Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України Experimental Oncology Short communications Tyrosine kinase inhibitors in treatment of fibrous histiocytoma Article published earlier |
| spellingShingle | Tyrosine kinase inhibitors in treatment of fibrous histiocytoma Maur, D. Panou, C. Valachis, A. Kamposioras, K. Tsali, L. Short communications |
| title | Tyrosine kinase inhibitors in treatment of fibrous histiocytoma |
| title_full | Tyrosine kinase inhibitors in treatment of fibrous histiocytoma |
| title_fullStr | Tyrosine kinase inhibitors in treatment of fibrous histiocytoma |
| title_full_unstemmed | Tyrosine kinase inhibitors in treatment of fibrous histiocytoma |
| title_short | Tyrosine kinase inhibitors in treatment of fibrous histiocytoma |
| title_sort | tyrosine kinase inhibitors in treatment of fibrous histiocytoma |
| topic | Short communications |
| topic_facet | Short communications |
| url | https://nasplib.isofts.kiev.ua/handle/123456789/135111 |
| work_keys_str_mv | AT maurd tyrosinekinaseinhibitorsintreatmentoffibroushistiocytoma AT panouc tyrosinekinaseinhibitorsintreatmentoffibroushistiocytoma AT valachisa tyrosinekinaseinhibitorsintreatmentoffibroushistiocytoma AT kamposiorask tyrosinekinaseinhibitorsintreatmentoffibroushistiocytoma AT tsalil tyrosinekinaseinhibitorsintreatmentoffibroushistiocytoma |