Image fusion using CT, MRI and PET for treatment planning, navigation and follow up in percutaneous RFA
Aim: To evaluate the feasibility of fusion of morphologic and functional imaging modalities to facilitate treatment planning, probe placement,
 probe re-positioning, and early detection of residual disease following radiofrequency ablation (RFA) of cancer. Methods: Multi-modality datasets&am...
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| Published in: | Experimental Oncology |
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| Date: | 2009 |
| Main Authors: | , , , , , , , , , |
| Format: | Article |
| Language: | English |
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Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
2009
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| Online Access: | https://nasplib.isofts.kiev.ua/handle/123456789/135704 |
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| Journal Title: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Cite this: | Image fusion using CT, MRI and PET for treatment planning, navigation and follow up in percutaneous RFA / F.L. Giesel, A. Mehndiratta, J. Locklin, M.J. McAuliffe, S. White, P.L. Choyke, M.V. Knopp, B.J. Wood, U. Haberkorn, H. von Tengg-Kobligk // Experimental Oncology. — 2009. — Т. 31, № 2. — С. 106-114. — Бібліогр.: 41 назв. — англ. |
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Digital Library of Periodicals of National Academy of Sciences of Ukraine| _version_ | 1862595959712645120 |
|---|---|
| author | Giesel, F.L. Mehndiratta, A. Locklin, J. McAuliffe, M.J. White, S. Choyke, P.L. Knopp, M.V. Wood, B.J. Haberkorn, U. von Tengg-Kobligk, H. |
| author_facet | Giesel, F.L. Mehndiratta, A. Locklin, J. McAuliffe, M.J. White, S. Choyke, P.L. Knopp, M.V. Wood, B.J. Haberkorn, U. von Tengg-Kobligk, H. |
| citation_txt | Image fusion using CT, MRI and PET for treatment planning, navigation and follow up in percutaneous RFA / F.L. Giesel, A. Mehndiratta, J. Locklin, M.J. McAuliffe, S. White, P.L. Choyke, M.V. Knopp, B.J. Wood, U. Haberkorn, H. von Tengg-Kobligk // Experimental Oncology. — 2009. — Т. 31, № 2. — С. 106-114. — Бібліогр.: 41 назв. — англ. |
| collection | DSpace DC |
| container_title | Experimental Oncology |
| description | Aim: To evaluate the feasibility of fusion of morphologic and functional imaging modalities to facilitate treatment planning, probe placement,
probe re-positioning, and early detection of residual disease following radiofrequency ablation (RFA) of cancer. Methods: Multi-modality datasets
were separately acquired that included functional (FDG-PET and DCE-MRI) and standard morphologic studies (CT and MRI). Different
combinations of imaging modalities were registered and fused prior to, during, and following percutaneous image-guided tumor ablation with
radiofrequency. Different algorithms and visualization tools were evaluated for both intra-modality and inter-modality image registration using
the software MIPAV (Medical Image Processing, Analysis and Visualization). Semi-automated and automated registration algorithms were used
on astandard PC workstation: 1) landmark-based least-squares rigid registration, 2) landmark-based thin-plate spline elastic registration, and
3) automatic voxel-similarity, affine registration. Results: Intra- and inter-modality image fusion were successfully performed prior to, during
and after RFA procedures. Fusion of morphologic and functional images provided a useful view of the spatial relationship of lesion structure and
functional significance. Fused axial images and segmented three-dimensional surface models were used for treatment planning and post-RFA
evaluation, to assess potential for optimizing needle placement during procedures. Conclusion: Fusion of morphologic and functional images
is feasible before, during and after radiofrequency ablation of tumors in abdominal organs. For routine use, the semi-automated registration
algorithms may be most practical. Image fusion may facilitate interventional procedures like RFA and should be further evaluated.
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| first_indexed | 2025-11-27T15:42:55Z |
| format | Article |
| fulltext | |
| id | nasplib_isofts_kiev_ua-123456789-135704 |
| institution | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| issn | 1812-9269 |
| language | English |
| last_indexed | 2025-11-27T15:42:55Z |
| publishDate | 2009 |
| publisher | Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України |
| record_format | dspace |
| spelling | Giesel, F.L. Mehndiratta, A. Locklin, J. McAuliffe, M.J. White, S. Choyke, P.L. Knopp, M.V. Wood, B.J. Haberkorn, U. von Tengg-Kobligk, H. 2018-06-15T14:08:05Z 2018-06-15T14:08:05Z 2009 Image fusion using CT, MRI and PET for treatment planning, navigation and follow up in percutaneous RFA / F.L. Giesel, A. Mehndiratta, J. Locklin, M.J. McAuliffe, S. White, P.L. Choyke, M.V. Knopp, B.J. Wood, U. Haberkorn, H. von Tengg-Kobligk // Experimental Oncology. — 2009. — Т. 31, № 2. — С. 106-114. — Бібліогр.: 41 назв. — англ. 1812-9269 https://nasplib.isofts.kiev.ua/handle/123456789/135704 Aim: To evaluate the feasibility of fusion of morphologic and functional imaging modalities to facilitate treatment planning, probe placement,
 probe re-positioning, and early detection of residual disease following radiofrequency ablation (RFA) of cancer. Methods: Multi-modality datasets
 were separately acquired that included functional (FDG-PET and DCE-MRI) and standard morphologic studies (CT and MRI). Different
 combinations of imaging modalities were registered and fused prior to, during, and following percutaneous image-guided tumor ablation with
 radiofrequency. Different algorithms and visualization tools were evaluated for both intra-modality and inter-modality image registration using
 the software MIPAV (Medical Image Processing, Analysis and Visualization). Semi-automated and automated registration algorithms were used
 on astandard PC workstation: 1) landmark-based least-squares rigid registration, 2) landmark-based thin-plate spline elastic registration, and
 3) automatic voxel-similarity, affine registration. Results: Intra- and inter-modality image fusion were successfully performed prior to, during
 and after RFA procedures. Fusion of morphologic and functional images provided a useful view of the spatial relationship of lesion structure and
 functional significance. Fused axial images and segmented three-dimensional surface models were used for treatment planning and post-RFA
 evaluation, to assess potential for optimizing needle placement during procedures. Conclusion: Fusion of morphologic and functional images
 is feasible before, during and after radiofrequency ablation of tumors in abdominal organs. For routine use, the semi-automated registration
 algorithms may be most practical. Image fusion may facilitate interventional procedures like RFA and should be further evaluated. This work was supported in part by the Intramural
 Research Program of the NIH.
 The authors thank Stephen Bacharach, MD, Ingmar
 Bitter, PhD and Grace Ko, MD for their support. en Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України Experimental Oncology Original contributions Image fusion using CT, MRI and PET for treatment planning, navigation and follow up in percutaneous RFA Article published earlier |
| spellingShingle | Image fusion using CT, MRI and PET for treatment planning, navigation and follow up in percutaneous RFA Giesel, F.L. Mehndiratta, A. Locklin, J. McAuliffe, M.J. White, S. Choyke, P.L. Knopp, M.V. Wood, B.J. Haberkorn, U. von Tengg-Kobligk, H. Original contributions |
| title | Image fusion using CT, MRI and PET for treatment planning, navigation and follow up in percutaneous RFA |
| title_full | Image fusion using CT, MRI and PET for treatment planning, navigation and follow up in percutaneous RFA |
| title_fullStr | Image fusion using CT, MRI and PET for treatment planning, navigation and follow up in percutaneous RFA |
| title_full_unstemmed | Image fusion using CT, MRI and PET for treatment planning, navigation and follow up in percutaneous RFA |
| title_short | Image fusion using CT, MRI and PET for treatment planning, navigation and follow up in percutaneous RFA |
| title_sort | image fusion using ct, mri and pet for treatment planning, navigation and follow up in percutaneous rfa |
| topic | Original contributions |
| topic_facet | Original contributions |
| url | https://nasplib.isofts.kiev.ua/handle/123456789/135704 |
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